Email this article Carane amino alcohols as organocatalysts in asymmetric aldol reaction of isatin with acetone
- Authors: Banina O.A.1, Sudarikov D.V.1, Nigmatov A.G.2, Frolova L.L.1, Slepukhin P.A.3, Zlotin S.G.2, Kutchin A.V.1
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Affiliations:
- Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences
- N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Issue: Vol 66, No 2 (2017)
- Pages: 293-296
- Section: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/240003
- DOI: https://doi.org/10.1007/s11172-017-1730-y
- ID: 240003
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Abstract
Carane-derived β-amino alcohols with amino and hydroxy groups at positions 3 and 4 differing in their mutual arrangement and configuration were synthesized. Their application as organocatalysts in the asymmetric aldol reaction of isatin with acetone allowed one to obtain adducts with up to 84% enantiomeric excess.
About the authors
O. A. Banina
Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences
Author for correspondence.
Email: olga.ferolg.banina@mail.ru
Russian Federation, 48 ul. Pervomaiskaya, Syktyvkar, 167000
D. V. Sudarikov
Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences
Email: olga.ferolg.banina@mail.ru
Russian Federation, 48 ul. Pervomaiskaya, Syktyvkar, 167000
A. G. Nigmatov
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: olga.ferolg.banina@mail.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
L. L. Frolova
Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences
Email: olga.ferolg.banina@mail.ru
Russian Federation, 48 ul. Pervomaiskaya, Syktyvkar, 167000
P. A. Slepukhin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: olga.ferolg.banina@mail.ru
Russian Federation, 22 ul. S. Kovalevskoi, Ekaterinburg, 620219
S. G. Zlotin
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: olga.ferolg.banina@mail.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
A. V. Kutchin
Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences
Email: olga.ferolg.banina@mail.ru
Russian Federation, 48 ul. Pervomaiskaya, Syktyvkar, 167000
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