Carane amino alcohols as organocatalysts in asymmetric aldol reaction of isatin with acetone


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Carane-derived β-amino alcohols with amino and hydroxy groups at positions 3 and 4 differing in their mutual arrangement and configuration were synthesized. Their application as organocatalysts in the asymmetric aldol reaction of isatin with acetone allowed one to obtain adducts with up to 84% enantiomeric excess.

作者简介

O. Banina

Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences

编辑信件的主要联系方式.
Email: olga.ferolg.banina@mail.ru
俄罗斯联邦, 48 ul. Pervomaiskaya, Syktyvkar, 167000

D. Sudarikov

Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences

Email: olga.ferolg.banina@mail.ru
俄罗斯联邦, 48 ul. Pervomaiskaya, Syktyvkar, 167000

A. Nigmatov

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: olga.ferolg.banina@mail.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991

L. Frolova

Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences

Email: olga.ferolg.banina@mail.ru
俄罗斯联邦, 48 ul. Pervomaiskaya, Syktyvkar, 167000

P. Slepukhin

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences

Email: olga.ferolg.banina@mail.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Ekaterinburg, 620219

S. Zlotin

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: olga.ferolg.banina@mail.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991

A. Kutchin

Institute of Chemistry, Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences

Email: olga.ferolg.banina@mail.ru
俄罗斯联邦, 48 ul. Pervomaiskaya, Syktyvkar, 167000

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