One-pot synthesis of cotarnine 1-alkynyl derivatives


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Abstract

Cotarnine chloride reacts with terminal acetylenes with short-time heating in acetonitrile in the presence of the catalytic system CuI—morpholine to form cotarnine 1-alkynyl derivatives.

About the authors

L. Yu. Ukhin

Institute of Physical and Organic Chemistry, Southern Federal University

Author for correspondence.
Email: may@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov on Don, 344090

E. N. Shepelenko

Southern Scientific Center, Russian Academy of Sciences

Email: may@ipoc.sfedu.ru
Russian Federation, 41 ul. Chekhova, Rostov on Don, 344006

L. V. Belousova

Institute of Physical and Organic Chemistry, Southern Federal University

Email: may@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov on Don, 344090

O. S. Popova

Institute of Physical and Organic Chemistry, Southern Federal University

Email: may@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov on Don, 344090

D. V. Alekseenko

Institute of Physical and Organic Chemistry, Southern Federal University

Email: may@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov on Don, 344090


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