Application of the DBSCAN Algorithm to Detect Hydrophobic Clusters in Protein Structures


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Аннотация

Hydrophobic cores and hydrophobic clusters play a key role in globular protein folding, providing a framework for functionally important amino acid residues of proteins and enzymes. A program was developed for clustering amino acid residues in protein structures, which takes into account their hydrophobicity and utilizes the DBSCAN algorithm. The program is described and its scope and applicability are outlined.

Авторлар туралы

A. Lashkov

Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Хат алмасуға жауапты Автор.
Email: alashkov83@gmail.com
Ресей, Moscow, 119333

S. Rubinsky

Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: alashkov83@gmail.com
Ресей, Moscow, 119333

P. Eistrikh-Heller

Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: alashkov83@gmail.com
Ресей, Moscow, 119333

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