Physical Methods for Determining the Phase Composition of Gallstones


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Gallstones with a zonal morphological structure have been studied using X-ray microtomography, X-ray diffraction analysis, Raman spectroscopy, and elemental analysis. Concrements have been investigated in vitro in the dried state; phases of cholesterol, bilirubin, calcium carbonate, and sodium and potassium chlorides are found in their composition. The analysis is performed within the development of tomographic methods, which can be used in future for intravital diagnostics of cholesterol cholelithiasis. The possibility of determining the phase composition of heterogeneous gallstones, based on the analysis of linear-absorption-coefficient distributions derived from X-ray monochromatic microtomography data, is demonstrated. The results of the tomographic analysis are in agreement with the data obtained using conventional direct methods for determining the phase and elemental composition of the objects under study.

作者简介

Y. Krivonosov

Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

编辑信件的主要联系方式.
Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Moscow, 119333

V. Asadchikov

Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Moscow, 119333

A. Buzmakov

Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Moscow, 119333

A. Ivanova

Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Moscow, 119333

V. Artemov

Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Moscow, 119333

A. Rusakov

Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Moscow, 119333

V. Pantyushov

Pirogov City Clinical Hospital No. 1

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Moscow

R. Saifutdinov

Department of Hospital and Polyclinic Therapy, Kazan State Medical Academy

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, Kazan

N. Minaev

Institute of Photonic Technologies, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, MoscowTroitsk, 108840

S. Minaeva

Institute of Photonic Technologies, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, MoscowTroitsk, 108840

M. Syachina

Institute of Photonic Technologies, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, MoscowTroitsk, 108840

V. Popov

Institute of Photonic Technologies, Federal Scientific Research Centre “Crystallography and Photonics,”
Russian Academy of Sciences

Email: Yuri.S.Krivonosov@yandex.ru
俄罗斯联邦, MoscowTroitsk, 108840

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