Hypoxia-inducible factor 1α in the central nervous system of the scallop Mizuhopecten yessoensis Jay, 1857 (Bivalvia: Pectinidae) during anoxia and elevated temperatures


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Аннотация

An immunocytochemical method was used to study the distribution of hypoxia-inducible factor 1α (HIF-1α) in the central nervous system (CNS) of the scallop Mizuhopecten yessoensis (Jay, 1857) (Bivalvia: Pectinidae) under anoxia and elevated temperatures. HIF-1α was not detected in the CNS of control mollusks. After 2 h anoxia, HIF-1α was detected in neurons of the cerebral and visceral ganglia. It was found that a change in HIF-1α immunoreactivity under anoxia had its own dynamics in each of the ganglia; these dynamics depended on the duration of anoxia and the temperature. The presented data indicate the involvement of the transcription factor HIF-1α in providing the compensatory processes that contribute to activation of the neuroprotective mechanisms in the nervous ganglia that control vital functions in M. yessoensis under short-term hypoxia.

Авторлар туралы

E. Kotsyuba

Zhirmunsky Institute of Marine Biology, National Scientific Center of Marine Biology, Far Eastern Branch

Хат алмасуға жауапты Автор.
Email: epkotsuba@mail.ru
Ресей, Vladivostok, 690041

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