Email this article Hypoxia during mammalian preimplantation development: Extreme circumstance vs. typical environment
- Authors: Pogorelov A.G.1, Smirnov A.A.1, Pogorelova V.N.1
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Affiliations:
- Institute of Theoretical and Experimental Biophysics
- Issue: Vol 47, No 2 (2016)
- Pages: 99-102
- Section: Embryogenesis and Carcinogenesis
- URL: https://journals.rcsi.science/1062-3604/article/view/183420
- DOI: https://doi.org/10.1134/S1062360416020077
- ID: 183420
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Abstract
The given paper summarizes the data on the early mammalian embryo development in culture media containing low oxygen concentration. Experimental results on in vitro modeling the hypoxia for preimplantation development are reviewed. Hypoxic conditions were shown to be available in the female reproductive tract of different mammalian species. The estimation of the embryo developing in vitro exhibits that lower oxygen level in culture media improves embryonic quality.
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About the authors
A. G. Pogorelov
Institute of Theoretical and Experimental Biophysics
Author for correspondence.
Email: agpogorelov@rambler.ru
Russian Federation, ul. Institutskaya 3, Pushchino, Moscow oblast, 142290
A. A. Smirnov
Institute of Theoretical and Experimental Biophysics
Email: agpogorelov@rambler.ru
Russian Federation, ul. Institutskaya 3, Pushchino, Moscow oblast, 142290
V. N. Pogorelova
Institute of Theoretical and Experimental Biophysics
Email: agpogorelov@rambler.ru
Russian Federation, ul. Institutskaya 3, Pushchino, Moscow oblast, 142290
