Micro-cloud point extraction for preconcentration of Aspirin in commercial tablets prior to spectrophotometric determination
- 作者: Kaykhaii M.1, Ghasemi E.1
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隶属关系:
- Department of Chemistry, Faculty of Sciences
- 期: 卷 71, 编号 8 (2016)
- 页面: 844-848
- 栏目: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182006
- DOI: https://doi.org/10.1134/S1061934816080074
- ID: 182006
如何引用文章
详细
A fast, simple, inexpensive and effective method is developed for spectrophotometric determination of Aspirin in commercial tablets based on micro-cloud point extraction (MCPE). The proposed MCPE is essentially a miniaturized form of traditional cloud point extraction (CPE) in which only a few microliters of micellar extracting phase is sufficient for spectrophotometric determination. For comparison with MCPE, cloud point extraction was examined for Aspirin extraction. Triton X-114 was employed as a non-ionic surfactant for extraction/preconcentration of aspirin. Factors influencing the extraction efficiency, such as concentration of Triton, effect of pH, type of dilution solvent, etc. were investigated and optimized. Under the optimized condition, linear calibration curve for MCPE was in the range of 0.05–2 mg/L and limit of detection of 0.05 mg/L was obtained, whereas linear part for CPE calibration curve was 0.9 to 11 mg/L with a limit of detection of 0.5 mg/L.
作者简介
Massoud Kaykhaii
Department of Chemistry, Faculty of Sciences
编辑信件的主要联系方式.
Email: kaykhaii@chem.usb.ac.ir
伊朗伊斯兰共和国, Zahedan, 98135-674
Elham Ghasemi
Department of Chemistry, Faculty of Sciences
Email: kaykhaii@chem.usb.ac.ir
伊朗伊斯兰共和国, Zahedan, 98135-674
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