Separation of 2-Bromobutane, 2-Chlorobutane, 2-Chloropentane, and 2-Butanol Enantiomers Using a Stationary Phase Based on a Supramolecular Uracil Structure
- Autores: Nafikova A.1, Allayarova D.1, Gus’kov V.1
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Afiliações:
- Department of Chemistry, Bashkir State University
- Edição: Volume 74, Nº 6 (2019)
- Páginas: 565-569
- Seção: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/183229
- DOI: https://doi.org/10.1134/S1061934819060078
- ID: 183229
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Resumo
We proposed a new chiral stationary phase based on a supramolecular uracil structure with induced chirality. According to the Kondepudi effect, mechanical stirring leads to the formation of a supramolecular structure layer on the surface of an adsorbent with a predominance of one of types of chiral supramolecular clusters. The obtained stationary phase was used for the gas-chromatographic separation of enantiomers of 2-bromobutane, 2-chlorobutane, 2-chloropentane, and 2-butanol. The effectiveness of a 1-m column packed with an inert stationary phase modified with uracil is 200–400 theoretical plates. The enantiomers of 2-bromobutane and 2-chlorobutane were completely separated using the proposed stationary phase in 210 and 180 s, respectively, at 45°C. The enantiomers of 2-chloropentane were separated at 60 and 65°C in 170 and 160 s, respectively. The enantiomers of 2-butanol were partially separated at 100°C. The enantioselectivity of the proposed stationary phase is probably associated with the adsorption of one enantiomer outside the cavity of the supramolecular structure and the other enantiomer inside it.
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Sobre autores
A. Nafikova
Department of Chemistry, Bashkir State University
Email: guscov@mail.ru
Rússia, Ufa, Bashkortostan, 450076
D. Allayarova
Department of Chemistry, Bashkir State University
Email: guscov@mail.ru
Rússia, Ufa, Bashkortostan, 450076
V. Gus’kov
Department of Chemistry, Bashkir State University
Autor responsável pela correspondência
Email: guscov@mail.ru
Rússia, Ufa, Bashkortostan, 450076