Deuterium Oxide (D2O) Determination in Water by Gas Chromatography–Mass Spectrometry Following Deuterium Exchange Headspace Extraction
- Autores: Jalal Hassan 1, Farahani A.2, Ramezani M.2
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Afiliações:
- Division of Toxicology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran
- Department of Chemistry, Arak Branch, Islamic Azad University
- Edição: Volume 73, Nº 8 (2018)
- Páginas: 796-800
- Seção: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182791
- DOI: https://doi.org/10.1134/S1061934818080063
- ID: 182791
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Resumo
A reliable, simple and fast method for quantitative analysis of heavy water (D2O) was developed using deuterium exchange headspace extraction–gas chromatography–mass spectrometry. The method is based on incubating the acetic anhydride with D2O, CH3COOD formation, headspace extraction of CH3COOD (exchange of hydrogen for deuterium) and gas chromatography/mass spectrometry detection. The quantification was performed using single ion monitoring (m/z = 61). The calibration was linear (R2 = 0.9998) in the concentration range of 1 × 103–3 × 105 mg/L). This method can measure D2O concentrations in water from 0.27 g/L. It was applied for determination of D2O in distilled water with accuracy RSD ≤ 6% and precision RSD ≤ 4%.
Sobre autores
Jalal Hassan
Division of Toxicology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran
Autor responsável pela correspondência
Email: jalalhassan@ut.ac.ir
Irã, Tehran
Abolfazl Farahani
Department of Chemistry, Arak Branch, Islamic Azad University
Email: jalalhassan@ut.ac.ir
Irã, Arak
Majid Ramezani
Department of Chemistry, Arak Branch, Islamic Azad University
Email: jalalhassan@ut.ac.ir
Irã, Arak