Determination of trace amounts of chlorobenzenes in water using membrane-supported headspace single-drop microextraction and gas chromatography–mass spectrometry
- Autores: Ma X.1, Ma J.2
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Afiliações:
- Department of Chromatography and Mass Spectrometry
- Department of Pharmacy
- Edição: Volume 72, Nº 8 (2017)
- Páginas: 890-896
- Seção: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182598
- DOI: https://doi.org/10.1134/S1061934817080135
- ID: 182598
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Resumo
A novel method based on the coupling of membrane-supported headspace single-drop microextraction with gas chromatography‒mass spectrometry (GC–MS) is developed for the determination of chlorobenzenes in water samples. For the determination of five chlorobenzenes, a 15 μL toluene microdrop was placed inside the plastic membrane and exposed for 10 min for headspace extraction while stirring at 1000 rpm. The microdrop was then picked up by a microsyringe and directly injected into the injector block of the GC–MS instrument. Under the optimized operation conditions, the calculated calibration curves gave a high level of linearity for all targets with correlation coefficients range from 0.9945 to 0.9987. The limits of detection range from 0.01 to 0.05 μg/L and the RSDs for most of chlorobenzenes were below 7%. The method is simple, sensitive, and stable for single drop microextraction. Its applicability is demonstrated by the determination of chlorobenzenes in tap water samples.
Sobre autores
Xiao Ma
Department of Chromatography and Mass Spectrometry
Email: majun369@126.com
República Popular da China, Shanghai, 201206
Jun Ma
Department of Pharmacy
Autor responsável pela correspondência
Email: majun369@126.com
República Popular da China, Lanzhou, 730050