Modeling of a new chromatographic system using the IONCHROM software and the choice of the optimum mode of chromatographic analysis

Resumo

Using the IONCHROM software, we performed modeling of a new chromatographic system on an example of an ion chromatograph from METROHM. To determine all necessary parameters, we had to construct a dynamic map of this system, by which the conditions of the required separation were found in different pH and concentration ranges, after which three or four experiments with the chosen eluents were sufficient. The model corrected with the the found parameters was used to predict the behavior of the system and, in particular, to optimize the analysis.