Graphene Quantum Dots Incorporated into β-cyclodextrin: a Novel Polymeric Nanocomposite for Non-Enzymatic Sensing of L-Tyrosine at Physiological pH
- Authors: Shadjou N.1,2, Hasanzadeh M.3, Talebi F.4
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Affiliations:
- Department of Nanochemistry, Nano Technology Research Center
- Department of Nano Technology, Faculty of Science
- Drug Applied Research Center
- Pharmaceutical Analysis Research Center and Faculty of Pharmacy
- Issue: Vol 73, No 6 (2018)
- Pages: 602-612
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/183073
- DOI: https://doi.org/10.1134/S1061934818060096
- ID: 183073
Cite item
Abstract
Graphene quantum dot-β-cyclodextrin modified glassy carbon electrode was used as a new nanosensor for determination of L-tyrosine (L-Tyr). It was found that graphene quantum dot-β-cyclodextrin has been stably electrodeposited on glassy carbon electrode modified by simple technique. The cyclic voltammograms of the modified electrode in an aqueous solution displayed a pair of well-defined, stable and irreversible reductive/oxidation redox systems. The apparent electron transfer rate constant (ks) and transfer coefficient (α) determined by cyclic voltammetry were approximately equal to 8.0 s–1 and 0.7, respectively. The modified electrode showed excellent catalytic activity towards the oxidation of L-Tyr at positive potential in buffer solution. The nanosensor also displayed fast response time, high sensitivity, low detection limit and a remarkably positive potential oxidation of L-Tyr that decreased the effect of interferences in analysis.
About the authors
Nasrin Shadjou
Department of Nanochemistry, Nano Technology Research Center; Department of Nano Technology, Faculty of Science
Email: mhmmd_hasanzadeh@yahoo.com
Iran, Islamic Republic of, Urmia, 57154; Urmia, 57154
Mohammad Hasanzadeh
Drug Applied Research Center
Author for correspondence.
Email: mhmmd_hasanzadeh@yahoo.com
Iran, Islamic Republic of, Tabriz, 51664
Faeze Talebi
Pharmaceutical Analysis Research Center and Faculty of Pharmacy
Email: mhmmd_hasanzadeh@yahoo.com
Iran, Islamic Republic of, Tabriz, 51664