Electrocatalytic determination of penicillamine using multiwall carbon nanotubes paste electrode and chlorpromazine as a mediator
- Authors: Keyvanfard M.1, Najjarian N.2, Alizad K.1
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Affiliations:
- Department of Chemistry, Majlesi Branch
- Department of Chemistry, Shahreza Branch
- Issue: Vol 72, No 10 (2017)
- Pages: 1045-1050
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182642
- DOI: https://doi.org/10.1134/S1061934817100136
- ID: 182642
Cite item
Abstract
In this study, we describe the application of carbon paste electrode modified with multiwall carbon nanotubes as a voltammetric sensor for determination of penicillamine (PA) in the presence of chlorpromazine as a mediator. This modified electrode showed very efficient electrocatalytic activity for the anodic oxidation of PA. The peak current of linear sweep voltammograms of PA increased linearly with it’s concentration in the range of 0.5–500 μM PA. The detection limit for PA was 0.2 μM. The RSDs for 1.0 and 10.0 μM PA were 1.1 and 1.7%, respectively. The proposed sensor was successfully applied for the determination of PA in human urine and tablet.
About the authors
Mohsen Keyvanfard
Department of Chemistry, Majlesi Branch
Author for correspondence.
Email: keyvan45638@yahoo.com
Iran, Islamic Republic of, Isfahan
Nazila Najjarian
Department of Chemistry, Shahreza Branch
Email: keyvan45638@yahoo.com
Iran, Islamic Republic of, Isfahan
Khadijeh Alizad
Department of Chemistry, Majlesi Branch
Email: keyvan45638@yahoo.com
Iran, Islamic Republic of, Isfahan