Voltammetric identification of insulin and its analogues using glassy carbon electrodes modified with polyarylenephthalides

Abstract

Using chemometrics, we developed a voltammetric method for the identification and discrimination of pharmaceuticals containing insulin and its analogues from various manufacturers. Their electrochemical behavior on glassy carbon electrodes modified with polyarylenephthalide films is studied; analytical characteristics are evaluated; and the optimal conditions for recording the analytical signal and the nature of electrode processes are determined. Some examples of the voltammetric identification and recognition of pharmaceutical products containing insulin are given.