Electrochemical methods for the determination of heparin
- Authors: Vishenkova D.A.1, Korotkova E.I.1
-
Affiliations:
- Institute of Natural Resources
- Issue: Vol 72, No 4 (2017)
- Pages: 349-353
- Section: Reviews
- URL: https://journals.rcsi.science/1061-9348/article/view/182362
- DOI: https://doi.org/10.1134/S1061934817040153
- ID: 182362
Cite item
Abstract
A review of studies on the determination of heparin in various samples (pharmaceuticals, biological fluids) by electrochemical methods of analysis in 1976–2014 is presented. Heparin is most often determined in pharmaceuticals by polarography using cationic dyes, and in biological samples, by differential pulse methods on non-stationary mercury electrodes. Works on the creation of heparin-selective electrodes coated with a polyvinylchloride membrane with quarternary ammonium salts are most promising; they can, probably, be used for the creation of portable devices for the determination of heparin.
Keywords
About the authors
D. A. Vishenkova
Institute of Natural Resources
Author for correspondence.
Email: vishenkova_darya@mail.ru
Russian Federation, Tomsk, 634050
E. I. Korotkova
Institute of Natural Resources
Email: vishenkova_darya@mail.ru
Russian Federation, Tomsk, 634050