Electrochemical determination of riboflavin using a synthesized ethyl[(methythio)carbonothioyl] glycinate monolayer modified gold electrode
- Authors: Karimian F.1, Rounaghi G.H.1, Mohadeszadeh M.1
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Affiliations:
- Department of Chemistry, Faculty of Sciences
- Issue: Vol 71, No 10 (2016)
- Pages: 1057-1062
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182126
- DOI: https://doi.org/10.1134/S1061934816080062
- ID: 182126
Cite item
Abstract
The surface of a gold disk electrode, for the first time, was modified with a self-assembled monolayer of a synthesized compound, ethyl [(methythio)carbonothioyl] glycinate (ECTG), for construction of an electrode sensitive to riboflavin (vitamin B2). The electrochemical properties of the monolayer assembled on the gold disk were investigated by cyclic voltammetry and electrochemical impedance spectroscopy. Under the optimized conditions, the voltammetric peak currents resulting from vitamin B2 (VB2) species were linear for VB2 concentrations in the range from 10–6 to 10–2 M. The effect of pH, type of buffer solution and scan rate on the response of the modified electrode was studied. The constructed electrochemical sensor responses very well to VB2 in the presence of most common vitamins. Finally, the performance of the Au–ECTG modified electrode was successfully tested for electrochemical detection of VB2 in a pharmaceutical sample.
About the authors
F. Karimian
Department of Chemistry, Faculty of Sciences
Email: ghrounaghi@yahoo.com
Iran, Islamic Republic of, Mashhad
G. H. Rounaghi
Department of Chemistry, Faculty of Sciences
Author for correspondence.
Email: ghrounaghi@yahoo.com
Iran, Islamic Republic of, Mashhad
M. Mohadeszadeh
Department of Chemistry, Faculty of Sciences
Email: ghrounaghi@yahoo.com
Iran, Islamic Republic of, Mashhad