Green analytical chemistry: Opportunities for pharmaceutical quality control
- Authors: Eldin A.B.1, Ismaiel O.A.2, Hassan W.E.2, Shalaby A.A.2
-
Affiliations:
- Sigma Pharmaceutical Industries
- Pharmaceutical Analytical Chemistry, Faculty of Pharmacy
- Issue: Vol 71, No 9 (2016)
- Pages: 861-871
- Section: Reviews
- URL: https://journals.rcsi.science/1061-9348/article/view/182027
- DOI: https://doi.org/10.1134/S1061934816090094
- ID: 182027
Cite item
Abstract
This review article summarizes the opportunities for utilizing the green analytical chemistry (GAC) techniques and principles in the field of quality control (QC) of pharmaceuticals. Green analytical chemistry is considered a branch of the green chemistry based on the principles overlapping with the goals of sustainable development. General definitions of quality and quality control, the principles of GAC, proposals for greener sample pretreatment and greener chromatographic method of analysis applied in QC laboratories are discussed herein. The main goal is to achieve more eco-friendly analysis in QC laboratories through different strategies and techniques, replace toxic reagents, and modify or replace analytical methods and/or techniques with safer ones, making it possible to dramatically reduce the amounts of reagents consumed and waste generated.
About the authors
A. B. Eldin
Sigma Pharmaceutical Industries
Author for correspondence.
Email: a.badr@sigma-pharm.com
Egypt, Quesna Industrial Zone, Menofia
O. A. Ismaiel
Pharmaceutical Analytical Chemistry, Faculty of Pharmacy
Email: a.badr@sigma-pharm.com
Egypt, Zagazig
W. E. Hassan
Pharmaceutical Analytical Chemistry, Faculty of Pharmacy
Email: a.badr@sigma-pharm.com
Egypt, Zagazig
A. A. Shalaby
Pharmaceutical Analytical Chemistry, Faculty of Pharmacy
Email: a.badr@sigma-pharm.com
Egypt, Zagazig