Clinical efficiency of intra-cavity biotherapy patients with malignant effusions


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The study evaluatedfeasibility, safety and effectiveness of cell biotherapy based on allogenic LAK-cells in combination with recombinant interleukin-2 (IL-2) used for sistem antitumor immunotherapy. The clinical study involved cancer patients with metastatic effusions resistant to systemic chemotherapy. The results showed that intra-cavity immunotherapy was highly effective and well tolerated in treatment of patients with malignant effusions.

作者简介

Konstantin Titov

N.N. blokhin Russian Cancer Research Center; N.I. Pirogov Russian National Research Medical University

Email: ks-titov@mail.ru
MD, PhD 115478, Moscow, Russian Federation

L. Demidov

N.N. blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

I. Shubina

N.N. blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

A. Gritsay

N.N. blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

A. Egorova

N.I. Pirogov Russian National Research Medical University

117997,Moscow, Russian Federation

M. Kiselevsky

N.N. blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

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