The role of ultrasonic diagnostics of liver metastates in designing surgical treatment strategy


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Aim. Determining the role of ultrasound examination in the diagnostics of liver metastases at the preoperative stage. Methods. 518 patients with secondary tumors in the liver underwent ultrasonic study (US). The results were compared with the data of other methods, biopsy, surgical palpation and histopathalogical study of the resected samples. Results. US strategy of metastasis diagnostics evaluates the number, size, and localization of lesions; the data remain valid for about a month. These data are used in surgery planning considering individual course of diseases and chemotherapy results. US metastasis diagnostics sensitivity, specificity and accuracy were 95.2%, 26.8%, 89.8%, respectively. We developed a methodology for accurate determination of lesion sites in the liver. The study showed that chemotherapy could worsen US results. The authors give practical recommendations for optimization ofpreoperative diagnostics. Conclusion. Ultrasound diagnostics demonstrated high effectiveness in determination of number, size, and precise localization of metastatic liver lesions that allows recommending this method for wide use in surgery planning.

作者简介

Tat’yana Danzanova

N.N. Blokhin Russian Cancer Research Center

Email: danzanova@yandex.ru
MD, PhD 115478, Moscow, Russian Federation

G. Sinyukova

N.N. Blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

E. Gudilina

N.N. Blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

V. Sholohov

N.N. Blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

P. Lepedatu

N.N. Blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

L. Kostyakova

N.N. Blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

G. Allahverdieva

N.N. Blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

S. Berdnikov

N.N. Blokhin Russian Cancer Research Center

115478, Moscow, Russian Federation

参考

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