Current strategies for diagnostics and treatment of lung and pleura metastasis


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Abstract

The frequency of lung metastases varies from 1.6 to 55.4% depending on the site and histological structure of the primary tumor according to the literature data. As a result of improving chemotherapy effectiveness, emergence of new diagnostic techniques, anesthesiology and surgical facilities, indications for lung metastases surgery are extending. The proportion of surgery for intrapulmonary metastases does not exceed 2.5 - 4% of all the thoracic surgeries despite the huge contingent of patients who require this specialized care. The complications rate after lung metastases surgery is about 10-15%. Mortality after surgery for lung metastases ranges from 1.2 to 6%.

About the authors

Bekzod B. Usmanov

National Cancer Research Center

Email: usmanov-83@mail.ru
MD 100074, Tashkent, Republic of Uzbekistan

References

  1. Харченко В.П., Котляров П.М., Глаголев Н.А. Лучевая диагностика образований переднего средостения. В кн.: Клиника, диагностика и лечение новообразований легких, средостения и плевры: Труды КОДМЗРТ. М.; 2002; т. 6: 148-50.
  2. Hwang J.H., Song K.S., Park S.I. Subtle pleural metastasis without large effusion in lung cancer patients: preoperative detection on CT. Korean J. Radiol. 2005; 6 (2): 94-101.
  3. Weinberg R.A. The Biology of Сancer. New York: Garland Science, 2007.
  4. Bryant A.S., McCarty Т. Non-imaged pulmonary nodules discovered during thoracotomy for metastasectomy by lung palpation. Eur. J. Cardiothorac. Surg. 2009; 35: 786-91.
  5. Трахтенберг А.Х., Паршин В.Д., Пикин О.В. Хирургическое лечение метастазов колоректального рака в легких. Российский онкологический журнал. 2005; 4: 18-21.
  6. Блинов Н.Н. Прогностические факторы в онкологии. Вопросы онкологии. 2001; 47 (3): 369-72.
  7. Чиссов В.И., Трахтенберг А.Х., Пикин О.В., Паршин В.Д. Метастатические опухоли легких. М.: Гэотар-Медиа; 2009: 101-9.
  8. Ганул В.Л., Бороров Л.В, Ганул А.В. и др. Целесообразность хирургического удаления метастазов злокачественных новообразований в легких. Клиническая онкология. 2012; 5 (1): 18-20.
  9. Ashida S., Furihata M., Tanimura M. et al. Molecular detection of Von Hippel-Lindau gene mutationsin urine and lymph node samples in patients with renal cell carcinoma: potential biomarkers for early diagnosisand postoperative matastatic status. J. Urol. 2003; 169: 2089-93.
  10. Ludwig C., Cerinza J., Passlick В., Stoelben E. Comparison of the number of pre-, intra- and postoperative lung metastases. Eur. J. Cardiothorac. Surg. 2008; 33: 470-2.
  11. Kozłowski J, Kozłowska A, Kocki J. Breast cancer metastasis - insight into selected molecular mechanisms of the phenomenon. Postepy Hig. Med. Dosw. (Online). 2015; 69 (0): 447-51.
  12. Li F., Li Q., Engelmann R, Aoyama M., Sone S., McMahon H., Doi K. Improving radiologists’ recommendations with computer - aided diagnosis for management of small nodules detected by CT. Acad. Radiol. 2006; 13(8): 943-50.
  13. Zompatori М., Sverzellati N., Poletti V. et al. High-resolution CT in diagnosis of diffuse infiltrative lung disease. Semin. Ultrasound, CT, MR. 2005; 26(5): 332-47.
  14. Nakas A., Ucar M., Edwards J.G., Waller D.A. The role of videoassisted thoracoscopic pleurectomy/decortication in the therapeutic management of malignant pleural mesothelioma. Eur. J. Cardiothorac. Surg. 2008; 33: 83-8.
  15. Rena O., Papalia E., Oliaro A., Filosso P.L., Ruffini E., Maggi G. et al. Pulmonary metastases from epithelial tumours: late results of surgical treatment. Eur. J. Cardiothorac. Surg. 2006; 30: 217-22.
  16. Varoli F., Vergani C., Caminiti R., Francese M., Gerosa C., Bongini M. et al. Management of solitary pulmonary nodule. Eur. J. Cardiothorac. Surg. 2008; 33: 461-5.
  17. Bezzi M., Forte A., Nasti G. et al. Surgical treatment of lung metastasis: experience with 108 cases. G. Chir. 2003; 24(1): 351-6.
  18. Sternberg D.I., Sonett J.R. Surgical therapy of lung metastases. Semin. Oncol. 2007; 34(3): 186-96.
  19. Minervini A., Lilas L., Morelli G., Traversi C. Regional lymph node dissection in the treatment of renal cell carcinoma: is it useful in patients with no suspected adenopathy before or during surgery? Br. J. Urol. Int. 2001; 88: 169.
  20. Buck D.A., Byrd R.H., Holmes C.L., Pollock T. Testicular metastasis in a case of squamous cell carcinoma of the lung. Case Rep. Oncol. 2015; 8 (1): 133-7.
  21. Welter S., Jacobs J., Krbek Т., Poettgen C., Stamatis G. Prognostic impact of lymph node involvement in pulmonary metastases from colorectal cancer. Eur. J. Cardiothorac. Surg. 2007; 31: 167-72.
  22. Андреяшкина И.И., Плохов В.Н. Комплексная диагностика метастазов рака молочной железы в легкие. Практическая медицина. 2007; 21: 18-9.
  23. Foukakis T., Lövrot J., Sandqvist P., Xie H., Lindström L.S., Giorgetti C. et al. Gene expression profiling of sequential metastatic biopsies for biomarker discovery in breast cancer. Mol. Oncol. 2015; pii: S1574-7891 (15) 00069-1.
  24. Луфт A.B. Клиническое обоснование хирургического лечения внутрилёгочных метастазов: Дисс. ... канд. мед. наук. СПб., 2001.
  25. Fialka C., Seitz H., Vecsei V. Primary therapy refractory osteomyelitis of the sternum after aortocoronary bypass operation - a case report. Zbl Chir. 2003; 121(10): 866-8.
  26. Сигал Е.Н., Хамидуллин Р.Г. Торакоскопическая хирургия. В кн.: Эндоскопическая хирургия / Под ред. И.В. Фёдорова и др. М.; 2001: 219-45.
  27. Nakajima J., Murakawa Т., Fukami Т., Sano A., Sugiura M., Takamoto S. Is finger palpation at surgery indispensable for pulmonary metastasectomy in colorectal cancer? Ann. Thorac. Surg. 2007; 84: 1680-4.
  28. Переводчикова Н.И., ред. Руководство по химиотерапии опухолевых заболеваний. М.: Практическая медицина; 2011.
  29. Timmerman R.D., Bizekis C.S., Pass H.I., Fong Y., Dupuy D.E., Dawson L.A. et al. Local surgical, ablative, and radiation treatment of metastases. CA. Cancer J. Clin. 2009; 59 (3): 145-70
  30. Hendriks J.M., Van Putte B., Romijn S. et al. Pneumonectomy for lung metastases: report often cases. Thorac. Cardiovasc. Surg. 2003; 51(l): 38-41.
  31. Yilmaz U., Polat G. CT in differential diagnosis of benign and malignant pleural disease. Monaldi Arch. Chest Dis. 2005; 63 (1): 17-22.

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