Surgical treatment of a metastatic melanoma patient after targeted therapy


Cite item

Full Text

Abstract

The article presents issues of diagnosis, course of disease, results of target therapy and surgery of a patient with metastatic melanoma Material and methods. Patient B., aged 19, referred to the department of tumors of the skin and soft tissues of COD № 1MOH KR with complaints on painful tumors in soft tissues of the body, right thigh and left inguinal area. On the basis of the examination she was diagnosed skin metastatic melanoma with multiple soft tissue lesions in the body, right thigh, left inguinal area and left ovary. The patient had surgical treatment: left laparoscopic adnexectomy, left inguinal-femoral lymphadenectomy, surgical excision of multiple soft tissue tumors in the body and right thigh. Results. We achieved a partial response to vemurafenib in the patient that allowed further surgical treatment. The postsurgical period was rather tolerable; the patient was discharged from the hospital under the surveillance of a cancer specialist near her place of residence.

About the authors

Sergey A. Yargunin

Clinical Oncology Dispensary №1

Email: sdocer@rambler.ru
MD, PhD 350040, Krasnodar, Russian Federation

E. V Semenihin

Clinical Oncology Dispensary №1

350040, Krasnodar, Russian Federation

References

  1. Демидов Л.В., Утяшев И.А., Харкевич Г.Ю. Роль вемурафениба в лечении диссеминированной меланомы кожи. Современная онкология. 2013; 15(2): 58-61.
  2. Орлова К.В., Харкевич Г.Ю., Демидов Л.В. Молекулярно-генетическая гетерогенность меланомы кожи и ее значение для разработки индивидуальных подходов к лечению. Фарматека. 2014; 17: 18-24.
  3. Проценко С.А., Новик А.В., Ахаева З.Ю., Жабина А.С., Имянитов Е.Н., Семенова А.И. Современные возможности персонализованной терапии метастатической меланомы кожи. Москва. Современная онкология. Репринт. 2014; 3: 3-10.
  4. Read J. Recent advances in cutaneous melanoma: towards a molecular model and targeted treatment. Australas. J. Dermatol. 2013. doi: 10.1111/ajd.12013. [Epub ahead of print] PMID: 23330781 [PubMed - as supplied by publisher].
  5. Du S.D., Mao Y.L., Li S.H., Sang X.T., Lu X., Xu Y.Y. et al. Surgical resection plus biotherapy/chemotherapy improves survival of hepatic metastaticmelanoma. World J. Hepatol. 2012; 4(11): 305-10. doi: 10.4254/wjh.v4.i11.305. PMID: 23293716 [PubMed] PMCID: PMC3536837.

Copyright (c) 2015 Eco-Vector


 


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies