LEVEL OF MATRIX METAL PROTEINAS AND THEIR TISSUE INHIBITORS IN WOMEN WITH NON-CARE OF PREGNANCY

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Surveyed 28 patients with sexually transmitted infections (STIs), or papillomavirus infection (PVI). The patients were divided into the main group (FG) and the control group (GC) (n = 10). The main group was divided into 2 groups: Group I (n = 8) ‒ STIs with MWI, Group II (n = 10) ‒ STIs without MWI. A simultaneous increase in MMP-9 and TIMP-1 in the serum of women with miscarriage was established, which indicates the role of the processes of damage to the extracellular matrix in its pathogenesis. Diff erences in the ratio of MMP-9 to TIMP-1 depending on the presence of HPV were revealed. Women with STIs without HPV are dominated by products of TIMP that can have a profibrinogenic eff ect.

作者简介

M. Tulupova

FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation

Email: fake@neicon.ru

Ph.D., Doctoral Candidate of the Department of Obstetrics and Gynecology with a course of Perinatology,

Vladivostok

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M. Hamoshin

FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation

Email: fake@neicon.ru

MD, Professor of the Department of Obstetrics and Gynecology with a course in Perinatology,

Vladivostok

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T. Nevezhkina

Pacific State Medical University, Ministry of Health of the Russian Federation

编辑信件的主要联系方式.
Email: www.tanya.ru9292@mail.ru

Post-Graduate Student, Department of Normal and Pathological Physiology,

Vladivostok

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O. Sidorova

Pacific State Medical University, Ministry of Health of the Russian Federation

Email: fake@neicon.ru

Ph.D., Associate Professor, Department of Normal and Pathological Physiology,

Vladivostok

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参考

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版权所有 © Tulupova M.S., Hamoshin M.B., Nevezhkina T.A., Sidorova O.N., 2019

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