LEVEL OF MATRIX METAL PROTEINAS AND THEIR TISSUE INHIBITORS IN WOMEN WITH NON-CARE OF PREGNANCY
- Authors: Tulupova M.S.1, Hamoshin M.B.1, Nevezhkina T.A.2, Sidorova O.N.2
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Affiliations:
- FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation
- Pacific State Medical University, Ministry of Health of the Russian Federation
- Issue: Vol 22, No 2-1 (2019)
- Pages: 581-583
- Section: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120308
- DOI: https://doi.org/10.31857/S102872210006981-4
- ID: 120308
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Abstract
Surveyed 28 patients with sexually transmitted infections (STIs), or papillomavirus infection (PVI). The patients were divided into the main group (FG) and the control group (GC) (n = 10). The main group was divided into 2 groups: Group I (n = 8) ‒ STIs with MWI, Group II (n = 10) ‒ STIs without MWI. A simultaneous increase in MMP-9 and TIMP-1 in the serum of women with miscarriage was established, which indicates the role of the processes of damage to the extracellular matrix in its pathogenesis. Diff erences in the ratio of MMP-9 to TIMP-1 depending on the presence of HPV were revealed. Women with STIs without HPV are dominated by products of TIMP that can have a profibrinogenic eff ect.
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About the authors
M. S. Tulupova
FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation
Ph.D., Doctoral Candidate of the Department of Obstetrics and Gynecology with a course of Perinatology,
Vladivostok
Russian FederationM. B. Hamoshin
FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation
MD, Professor of the Department of Obstetrics and Gynecology with a course in Perinatology,
Vladivostok
Russian FederationT. A. Nevezhkina
Pacific State Medical University, Ministry of Health of the Russian Federation
Author for correspondence.
Email: www.tanya.ru9292@mail.ru
Post-Graduate Student, Department of Normal and Pathological Physiology,
Vladivostok
Russian FederationO. N. Sidorova
Pacific State Medical University, Ministry of Health of the Russian Federation
Ph.D., Associate Professor, Department of Normal and Pathological Physiology,
Vladivostok
Russian FederationReferences
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