FEATURES OF LUMINAL-DEPENDENT CHEMILUMINESCENCE REACTION UNER THE COLD STRESS. OPIATE MECHANISMS

Acute cold stress (4°C, 4 hours) led to inhibition of the production of ROS (reactive oxygen species) in stimulated cultures of peritoneal macrophages of the mouse. The effect of acute cold stress was not modified by the administration of naloxone. Chronic cold stress (4°C, 4 hours, 7 days) led to stimulation of ROS production by peritoneal macrophages of mice in the presence of zymosan. This effect is partially canceled by the administration of naloxone.

перитонеальные макрофаги, хемилюминесценция, холодовой стресс, peritoneal macrophages, hemiluministention, cold stress