FUNCTIONAL ACTIVITY OF MONOCYTES IN PREMATURE INFANTS IN NEONATAL DYNAMICS
- 作者: Remizova I.1, Shamova K.1, Chistyakova G.1
-
隶属关系:
- FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
- 期: 卷 20, 编号 3 (2017)
- 页面: 480-482
- 栏目: Articles
- URL: https://journals.rcsi.science/1028-7221/article/view/119782
- ID: 119782
如何引用文章
全文:
详细
To assess the functional activity of monocytes in preterm infants of different gestational age (22-27.6 weeks and 28-31 weeks) in the dynamics of the neonatal period, cord and peripheral blood were examined. All children with an ENMT at birth had a decreased willingness of effector cells to participate in intercellular interactions (decrease in the number of CD14+ CB 282+ and CD14+ CD157+ monocytes), in infants of gestational age 22-27 weeks - to antigen presentation of the pathogen (decrease in HLA receptor expression -DR+). At the end of the neonatal period, the functional activity of monocytes is restored, the number of CD14+ HLA-DR+ cells exceeds those of full-term children.
作者简介
I. Remizova
FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: noemail@neicon.ru
俄罗斯联邦
K. Shamova
FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
Email: noemail@neicon.ru
俄罗斯联邦
G. Chistyakova
FGBU “Ural Scientific Research Institute for Maternal and Infant Childhood Protection", Ministry of Health of the Russian Federation
Email: noemail@neicon.ru
俄罗斯联邦
参考
- Zhang J., Zhou J., Xu B., Chen C., Shi W. Different expressions of TLRs and related factors in peripheral blood of preterm infants. Int J Clin Exp Med. 2015, 8(3), 4108-4114.
- Li Y., Wei Q.F., Pan X.N., Meng D.H., Liu X.Z., Xu J., Wei W. Cellular and humoral immunity in preterm infants of different gestational ages. Zhongguo Dang Dai Er Ke Za Zhi 2014, 16(11), 1118-1121.
- Володин Н. Н., Дегтярев Д. Н., Байбарина Е. Н. Неонатология: Учебное пособие. ГЭОТАР- Медиа, Москва, 2008, 116-122.
- Топтыгина А. П., Семикина Е. Л., Копыльцо-ва Е. А., Алешкин В. А. Возрастные особенности формирования гуморального звена иммунного ответа у детей. Медицинская иммунология, 2012, 14(4-5), 289-294.
- Quinello C., Silveira-Lessa A.L., Ceccon M.E. et al. Phenotypic differences in leucocyte populations among healthy preterm and full-term newborns. Scand J Immunol. 2014 Jul; 80(1):57-70.
