PREVALENCE OF ANTINUCLEAR ANTIBODY IN CHILDREN WITH REACTIVE ARTHRITIS
- 作者: Krivolapova I.1,2, Pashnina I.1,2, Chereshnev V.2
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隶属关系:
- Regional Child's Clinical Hospital № 1
- Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
- 期: 卷 20, 编号 3 (2017)
- 页面: 398-400
- 栏目: Articles
- URL: https://journals.rcsi.science/1028-7221/article/view/119582
- ID: 119582
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Children with reactive arthritis (n=26) of 2-17 years old were examinated. Antinuclear antibodies were determined by indirect immunofluorescence assay, antibodies to extractable nuclear antigens were defined by ELISA. It was found that 12 patients (46 %) with reactive arthritis had diagnostic titers of antinuclear antibodies detected by indirect immunofluorescence assay. Homogeneous and speckled fluorescence patterns were observed in patients with reactive arthritis. The prevalence of antibodies to extractable nuclear antigens in children with reactive arthritis was low (8 %).
作者简介
I. Krivolapova
Regional Child's Clinical Hospital № 1; Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
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Email: noemail@neicon.ru
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I. Pashnina
Regional Child's Clinical Hospital № 1; Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
Email: noemail@neicon.ru
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V. Chereshnev
Institute of Immunology and Physiology Ural Branch of the Russian Academy of Sciences
Email: noemail@neicon.ru
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参考
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- Пашнина И. А., Криволапова И. М., Козло ва Е. С., Скоробогатова О. В., Тузанкина И. А., Черешнев В. А. Аутоантитела при ювенильных артритах у детей. Российский иммунологический журнал 2013, том 7(16), 4, 437-444.
- Алексеева Е. И., Чистякова Е. Г. Реактивный артрит. В кн.: Педиатрия: национальное руководство краткое издание. ГЭОТАР-Медиа, Москва 2014,177-196.
- Malleson P. N., Sailer M., Machinnon M. J. Useful-lness of antinuclear antibody testing to screen for rheumatic diseases. Archives of Disease in Childhood. 1997, 77, 299-304.
- Лапин С. В., Тотолян А. А. Иммунологическая лабораторная диагностика аутоиммунных заболеваний. Человек, Санкт-Петербург 2010, 272.
