Cerebral mechanisms in genesis of paroxysmal disorders

The possibility of existence of nonspecific cerebral mechanisms, providing the development of paroxysmal disorders, has been studied. Nonspecific pattern of bioelectric activity has been revealed, typical of paroxysmal conditions both of epileptic and nonepileptic character and different from indices of normal brain and brain of patients with permanent disorders which allows to discuss the existence of “paroxysmal brain”. The results of the investigations give reason to assert, that change of functional state of brain — insufficiency of activity and disbalance of activation system, which facilitate the persistence of excitation of cortical neurons — is a main risk factor of formation of “paroxysmal brain”.