Email this article The ability to recognize odors in patients suffering from the schizophrenia spectrum disorders and depressive disorders
- Authors: Dmitrieva N.G.1,2, Shunenkov D.A.3, Enikolopov S.N.4
-
Affiliations:
- Psychiatric Hospital No. 1 named after N.A. Alexeev
- Mental Health Research Center
- Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
- Scientific Institution of Mental Health Research Center
- Issue: Vol LIII, No 1 (2021)
- Pages: 19-22
- Section: Original study arcticles
- URL: https://journals.rcsi.science/1027-4898/article/view/58803
- DOI: https://doi.org/10.17816/nb58803
- ID: 58803
Cite item
Open Access
Access granted
Subscription Access
Abstract
The works’ purpose was to study connection between smell malfunction that reduces level of smell recognition (anosmia) and current emotional condition of patients who suffer from schizophrenia spectrum disorders and patients with depressive disorders.
Methods of research. Patients who suffer from schizophrenia spectrum disorders (F20, F21, F23, F25), depressive disorders (F32, F33), and healthy individuals were examined. Methods of evaluation of current emotional condition were Beck Depression Inventory and Snaith–Hamilton Pleasure Scale. To determine malfunction of smell function “Professional olfactometric set of odorous substances “RAMORA” was used.
Results. In patients with schizophrenia spectrum disorders, the level of smell recognition is significantly lower than in the group of patients suffering from depressive disorders and the group of healthy people. When comparing patients with depressive disorders with a group of healthy individuals, there is a slight decrease in the identification of odors, close to normal values. In patients with depressive disorders and patients with schizophrenia, an increase in the level of anhedonia and depression is detected in comparison with healthy subjects. The overall level of smell recognition is not related to the indicators of the current emotional state (depression and anhedonia) in both clinical groups. However, the relationships between the identification of individual odorants and the actual emotional state in the group of patients with schizophrenia spectrum disorders were revealed.
Conclusions. A decrease in the level of odor identification (anosmia) is observed in patients with schizophrenia spectrum. These disorders are not typical for patients with depressive disorders and people who do not suffer from mental illness. The obtained results require additional research. It can be assumed that the indicators of olfactory processes can be an additional diagnostic method of the emotional and personal sphere of patients with the schizophrenia spectrum disorders.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
Nadezhda G. Dmitrieva
Psychiatric Hospital No. 1 named after N.A. Alexeev; Mental Health Research Center
Author for correspondence.
Email: alennoss@gmail.com
ORCID iD: 0000-0003-0040-5537
Russian Federation, 117152, Moscow, Zagorodnoe shosse, 2; Mental Health Research Center
Denis A. Shunenkov
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
Email: voksined@yandex.ru
Russian Federation, 141534, Moscow region, Solnechnogorsk district, Lytkino village, 777
Sergej N. Enikolopov
Scientific Institution of Mental Health Research Center
Email: enikolopov@mail.ru
ORCID iD: 0000-0002-7899-424X
SPIN-code: 6911-9855
ResearcherId: C-2922-2016
PhD, Professor, Head of Clinical Psychology Department
Russian Federation, 115522, Moscow, Kashirskoye shosse, 34References
- Turetsky B.I., Kohler C.G., Gur R.E., Moberg P.J. Olfactory physiological impairment in first-degree relatives of schizophrenia patients. Schizophr. Res. 2008; 102 (1–3): 220–229.
- Takahashi T., Wood S.J., Yung A.R. et al. Altered depth of the olfactory sulcus in ultra high-risk individuals and patients with psychotic disorders. Schizophr. Res. 2014; 153 (1–3): 18–24. doi: 10.1016/j.schres.2014.01.041. PMID: 24530137.
- Борисенко Г.Н. Распространённость, особенности клинического течения и диагностики заболеваний носа и околоносовых пазух у больных шизофренией. Дисс ... кандидата мед. наук: 14.00.04. ФГУ Российский научно-практический центр аудиологии и слухопротезирования. М. 2005; 115 с. [Borisenko G.N. Rasprostranennostʹ, osobennosti klinicheskogo techeniya i diagnostiki zabolevaniy nosa i okolonosovykh pazukh u bolʹnykh shizofreniey. Diss ... kandidata med. nauk: 14.00.04. FGU Rossiyskiy nauchno-prakticheskiy tsentr audiologii i slukhoprotezirovaniya. M. 2005; 115 р. (In Russ.)]
- Дмитриева Н.Г., Ениколопов С.Н. Нарушения обоняния при психических расстройствах. Социал. и клин. психиатрия. 2019; (4): 96–99. [Dmitrieva N.G., Enikolopov S.N. Narusheniya obonyaniya pri psikhicheskikh rasstroystvakh. Sotsialʹnaya i klinicheskaya psikhiatriya. 2019; (4): 96–99. (In Russ.)]
- Kamath V., Lasutschinkow P., Ishizuka K., Sawa A. Olfactory functioning in first-episode psychosis. Schizophr. Bull. 2018; 44 (3): 672–680.
- Negoias S., Croy I., Gerber J. et al. Reduced olfactory bulb volume and olfactory sensitivity in patients with acute major depression. Neuroscience. 2010; 169: 415–421.
- Pause B.M., Miranda A., Göder R. et al. Reduced olfactory performance in patients with major depression. J. Psychiatr. Res. 2001; 35: 271–277.
- Rochet M., El-Hage W., Richa S. et al. Depression, olfaction, and quality of life: A mutual relationship. Brain Sci. 2018; 8 (5): 80.
- Богданов В.Вас., Завадский А.В., Богданов В.Влад. Анатомофизиологические особенности обонятельного анализатора и современные методы диагностики нарушения обоняния. Ринологія. 2013; (3): 65–82. [Bogdanov V.Vas., Zavadskiy A.V., Bogdanov V.Vlad. Anatomofiziologicheskie osobennosti obonyatelʹnogo analizatora i sovremennye metody diagnostiki narusheniya obonyaniya. Rinologіya. 2013; (3): 65–82. (In Russ.)]
Supplementary files
