Cognitive impairment in patients on hemodialysis

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Abstract

The aim of research was to study cognitive impairment (CI) in patients on hemodialysis (HD): 63 people (25 men and 38 women) aged 38 to 72 years (mean age 54. 2±11. 1 years). The main group consisted of 43 people on HD. The control group consisted of 20 relatively healthy individuals without kidney disease. A clinical neurological examination, MoCA and Mini-Cog tests were conducted. It was found that CI are much more common in patients on HD (according to MoCA, 81. 4%; Mini-Cog, 34. 9%). The inverse dependence of the cognitive status on the duration of dialysis patients was demonstrated (r=-0. 27, p≤0. 05). A weak correlation between MoCA test and the adequacy of the dialysis dose (kt/V index) was detected. The structure of CI in HD patients was dominated by memory impairment, visual-constructive disorders, changes in the executive skills and fluency of speech.

About the authors

Alexey E. Khrulev

Privolzhsky Research Medical University

Author for correspondence.
Email: alexey_khrulev@mail.ru

кафедра неврологии, нейрохирургии и медицинской генетики

Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1

Svetlana F. Studyanikova

Privolzhsky Research Medical University

Email: alexey_khrulev@mail.ru

кафедра неврологии, нейрохирургии и медицинской генетики

Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1

Svetlana V. Langraf

Privolzhsky Research Medical University

Email: alexey_khrulev@mail.ru

кафедра неврологии, нейрохирургии и медицинской генетики

Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1

Roman V. Sadyrin

Privolzhsky Research Medical University

Email: alexey_khrulev@mail.ru

кафедра неврологии, нейрохирургии и медицинской генетики

Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1

Vera N. Grigoryeva

Privolzhsky Research Medical University

Email: alexey_khrulev@mail.ru

кафедра неврологии, нейрохирургии и медицинской генетики

Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1

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Supplementary files

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2. Fig. 1. The structure of cognitive impairment in patients receiving PG (according to MoCA)

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Copyright (c) 2019 Khrulev A.E., Studyanikova S.F., Langraf S.V., Sadyrin R.V., Grigoryeva V.N.

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