Cognitive impairment in patients on hemodialysis
- Authors: Khrulev A.E.1, Studyanikova S.F.1, Langraf S.V.1, Sadyrin R.V.1, Grigoryeva V.N.1
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Affiliations:
- Privolzhsky Research Medical University
- Issue: Vol LI, No 2 (2019)
- Pages: 36-40
- Section: Original study arcticles
- URL: https://journals.rcsi.science/1027-4898/article/view/15659
- DOI: https://doi.org/10.17816/nb15659
- ID: 15659
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Abstract
The aim of research was to study cognitive impairment (CI) in patients on hemodialysis (HD): 63 people (25 men and 38 women) aged 38 to 72 years (mean age 54. 2±11. 1 years). The main group consisted of 43 people on HD. The control group consisted of 20 relatively healthy individuals without kidney disease. A clinical neurological examination, MoCA and Mini-Cog tests were conducted. It was found that CI are much more common in patients on HD (according to MoCA, 81. 4%; Mini-Cog, 34. 9%). The inverse dependence of the cognitive status on the duration of dialysis patients was demonstrated (r=-0. 27, p≤0. 05). A weak correlation between MoCA test and the adequacy of the dialysis dose (kt/V index) was detected. The structure of CI in HD patients was dominated by memory impairment, visual-constructive disorders, changes in the executive skills and fluency of speech.
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##article.viewOnOriginalSite##About the authors
Alexey E. Khrulev
Privolzhsky Research Medical University
Author for correspondence.
Email: alexey_khrulev@mail.ru
кафедра неврологии, нейрохирургии и медицинской генетики
Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1Svetlana F. Studyanikova
Privolzhsky Research Medical University
Email: alexey_khrulev@mail.ru
кафедра неврологии, нейрохирургии и медицинской генетики
Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1Svetlana V. Langraf
Privolzhsky Research Medical University
Email: alexey_khrulev@mail.ru
кафедра неврологии, нейрохирургии и медицинской генетики
Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1Roman V. Sadyrin
Privolzhsky Research Medical University
Email: alexey_khrulev@mail.ru
кафедра неврологии, нейрохирургии и медицинской генетики
Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1Vera N. Grigoryeva
Privolzhsky Research Medical University
Email: alexey_khrulev@mail.ru
кафедра неврологии, нейрохирургии и медицинской генетики
Russian Federation, 603005, Nizhny Novgorod, Minin and Pozharsky sq., 10/1References
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