A. I. Yushchenko. Catatonic-like symptoms in dogs lacking a thyroid gland. To the physiology of the thyroid gland. — Review of Psychiatry, Neurology and Experimental Psychology. 1910 № 2

After complete thyroidectomy in dogs, the author observed muscle rigidity, trembling; simple and more complex monotonous movements, salivation, lowering of temperature; further, a passive attitude to everything around, lethargy and some. other phenomena. The urine and serum of such animals are more poisonous than those of normal ones; oxidative functions of the blood are lowered. A milk diet and bowel cleansing temporarily improves the condition of animals deprived of the thyroid gland, but all of them soon die from convulsive seizures with symptoms of intoxication and mental depression.