Lipid-correcting and antioxidant effects of the lipid complex from the red marine algae Ahnfeltia tobuchiensis under the conditions of a high-fat diet

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Abstract

The influence of the lipid complex isolated from the thallus of the red marine algae Ahnfeltia tobuchiensis (LCA) on the metabolic parameters of the blood and liver of rats under a high-fat diet was studied. It was shown that the administration of LCA had a pronounced lipid-correcting and antioxidant effect, which was superior to that of the reference preparation “Omega 3-6-9” in terms of its ability to restore lipid metabolism, the ratio of lipoprotein fractions and the indices of the endogenous antioxidant protection system, as so as prevent the development of hepatosis. The lipid-correcting and anti-oxidant effect of LCA is specified by the action of n-3 polyunsaturated fatty acids, in particular eicosapentaenoic acid, which are the part of the structure of phospholipids and glycolipids of marine origin, which make up the main part of the studied lipid complex.

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V. G. Sprygin

V.I. Il’ichev Pacific Oceanological Institute FEB RAS

Email: vgs2006@mail.ru
Russian Federation, Vladivostok, 690041

Н. Ф. Kushnerova

V.I. Il’ichev Pacific Oceanological Institute FEB RAS

Email: vgs2006@mail.ru
Russian Federation, Vladivostok, 690041

S. E. Fomenko

V.I. Il’ichev Pacific Oceanological Institute FEB RAS

Email: vgs2006@mail.ru
Russian Federation, Vladivostok, 690041

E. S. Drugova

V.I. Il’ichev Pacific Oceanological Institute FEB RAS

Email: vgs2006@mail.ru
Russian Federation, Vladivostok, 690041

L. N. Lesnikova

V.I. Il’ichev Pacific Oceanological Institute FEB RAS

Email: vgs2006@mail.ru
Russian Federation, Vladivostok, 690041

V. Yu. Merzlyakov

V.I. Il’ichev Pacific Oceanological Institute FEB RAS

Author for correspondence.
Email: vgs2006@mail.ru
Russian Federation, Vladivostok, 690041

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2. Fig. 1. The content of lipid fractions (mmol/l) in the blood plasma of rats under high-fat diet (HFD) with the administration of a lipid complex from A. tobuchiensis and the Omega drug. The differences are significant (p < 0.05) compared with the control – *, with the HJD group – #, with the HZD + ahnfelcia group – +

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3. Fig. 2. The content of neutral lipid fractions (% of the sum of fractions) in the liver of rats under conditions of a high-fat diet (HFD) with the introduction of a lipid complex from A. tobuchiensis and the Omega drug. The differences are significant (p < 0.05) compared with the control – *, with the HJD group – #, with the HZD + Ahnfeltsiya group – +

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