Genetic Aspects of Drug Resistance and Virulence in Mycobacterium tuberculosis
- 作者: Shur K.1, Bekker O.1, Zaichikova M.1, Maslov D.1, Akimova N.1, Zakharevich N.1, Chekalina M.1, Danilenko V.1
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隶属关系:
- Vavilov Institute of General Genetics Russian Academy of Sciences
- 期: 卷 54, 编号 12 (2018)
- 页面: 1385-1396
- 栏目: Reviews and Theoretical Articles
- URL: https://journals.rcsi.science/1022-7954/article/view/188698
- DOI: https://doi.org/10.1134/S1022795418120141
- ID: 188698
如何引用文章
详细
Drug-resistant Mycobacterium tuberculosis and its high virulence new strains present a global health threat. The solution of this problem requires the development of new anti-tuberculosis drugs. Investigation of the genetic mechanisms associated with the development of multidrug resistant M. tuberculosis strains is the basis for the search for new biotargets of anti-tuberculosis drugs. To date, the molecular genetic relationships between genes controlling drug resistance and virulence remain poorly investigated and require special attention. In the present study, genetic mechanisms of interaction of genetic systems of drug resistance and virulence of M. tuberculosis are considered.
作者简介
K. Shur
Vavilov Institute of General Genetics Russian Academy of Sciences
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991
O. Bekker
Vavilov Institute of General Genetics Russian Academy of Sciences
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991
M. Zaichikova
Vavilov Institute of General Genetics Russian Academy of Sciences
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991
D. Maslov
Vavilov Institute of General Genetics Russian Academy of Sciences
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991
N. Akimova
Vavilov Institute of General Genetics Russian Academy of Sciences
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991
N. Zakharevich
Vavilov Institute of General Genetics Russian Academy of Sciences
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991
M. Chekalina
Vavilov Institute of General Genetics Russian Academy of Sciences
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991
V. Danilenko
Vavilov Institute of General Genetics Russian Academy of Sciences
编辑信件的主要联系方式.
Email: valerid@vigg.ru
俄罗斯联邦, Moscow, 119991