Current technics for visualizing RNA in a cell
- 作者: Ibragimov A.1, Kozlov E.1, Kurbidaeva A.1, Ryabichko S.1, Shidlovskii Y.1,2
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隶属关系:
- Institute of Gene Biology
- Department of Biology and General Genetics
- 期: 卷 53, 编号 10 (2017)
- 页面: 1080-1090
- 栏目: Reviews and Theoretical Articles
- URL: https://journals.rcsi.science/1022-7954/article/view/188468
- DOI: https://doi.org/10.1134/S1022795417100040
- ID: 188468
如何引用文章
详细
The study of RNA functions in a cell is based on the methods of labeling and detection of these molecules. In recent years, considerable progress has been made in this area, making it possible to detect RNA in amounts to one molecule with high specificity and to track the dynamics of spatial RNA distribution in the living cell. The review presents the latest developments in the field of in situ hybridization and the use of RNA aptamers and RNA-binding proteins. The prospects of using the CRISPR-Cas system for RNA visualization are discussed in detail.
作者简介
A. Ibragimov
Institute of Gene Biology
Email: yul.biogen@gmail.com
俄罗斯联邦, Moscow, 119334
E. Kozlov
Institute of Gene Biology
Email: yul.biogen@gmail.com
俄罗斯联邦, Moscow, 119334
A. Kurbidaeva
Institute of Gene Biology
Email: yul.biogen@gmail.com
俄罗斯联邦, Moscow, 119334
S. Ryabichko
Institute of Gene Biology
Email: yul.biogen@gmail.com
俄罗斯联邦, Moscow, 119334
Yu. Shidlovskii
Institute of Gene Biology; Department of Biology and General Genetics
编辑信件的主要联系方式.
Email: yul.biogen@gmail.com
俄罗斯联邦, Moscow, 119334; Moscow, 119048