Fundamentally low reproducibility in molecular genetic cancer research
- 作者: Alekseenko I.V.1, Pleshkan V.V.1, Monastyrskaya G.S.1, Kuzmich A.I.1, Snezhkov E.V.1, Didych D.A.1, Sverdlov E.D.1
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隶属关系:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- 期: 卷 52, 编号 7 (2016)
- 页面: 650-663
- 栏目: Article
- URL: https://journals.rcsi.science/1022-7954/article/view/187774
- DOI: https://doi.org/10.1134/S1022795416070036
- ID: 187774
如何引用文章
详细
The review discusses the causes of multiple failures in cancer treatment, which might primarily result from the excessive variability of cancer genomes. They are capable of changing their spatial and temporal architecture during tumor development. The key reasons of irreproducibility of biomedical data and the presumable means for improvement of therapeutic results aiming at targeting the most stable tumor traits are suggested.
作者简介
I. Alekseenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
编辑信件的主要联系方式.
Email: irina.alekseenko@mail.ru
俄罗斯联邦, Moscow, 117997
V. Pleshkan
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: irina.alekseenko@mail.ru
俄罗斯联邦, Moscow, 117997
G. Monastyrskaya
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: irina.alekseenko@mail.ru
俄罗斯联邦, Moscow, 117997
A. Kuzmich
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: irina.alekseenko@mail.ru
俄罗斯联邦, Moscow, 117997
E. Snezhkov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: irina.alekseenko@mail.ru
俄罗斯联邦, Moscow, 117997
D. Didych
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: irina.alekseenko@mail.ru
俄罗斯联邦, Moscow, 117997
E. Sverdlov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: irina.alekseenko@mail.ru
俄罗斯联邦, Moscow, 117997
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