Genetic control of circadian rhythms and aging
- 作者: Solovyov I.1,2, Dobrovol’skaya E.1, Moskalev A.1,2,3,4
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隶属关系:
- Institute of Biology, Komi Research Center, Ural Branch
- Department of Biology
- Moscow Institute of Physics and Technology
- Vavilov Institute of General Genetics
- 期: 卷 52, 编号 4 (2016)
- 页面: 343-361
- 栏目: Reviews and Theoretical Articles
- URL: https://journals.rcsi.science/1022-7954/article/view/187672
- DOI: https://doi.org/10.1134/S1022795416040104
- ID: 187672
如何引用文章
详细
The review establishes a link between a group of genes which are conserved in evolution and form a molecular oscillator responsible for generation of circadian rhythms and genetic determinants of aging including associated pathways of intracellular signaling. An analysis of mechanisms of development of agedependent pathologies is conducted from the viewpoint of circadian genetics. Systematic data of circadian gene expression studies in animals demonstrating different rates of aging from accelerated to negligible are presented.
作者简介
I. Solovyov
Institute of Biology, Komi Research Center, Ural Branch; Department of Biology
编辑信件的主要联系方式.
Email: amoskalev@ib.komisc.ru
俄罗斯联邦, Syktyvkar, 167000; Syktyvkar, 167001
E. Dobrovol’skaya
Institute of Biology, Komi Research Center, Ural Branch
Email: amoskalev@ib.komisc.ru
俄罗斯联邦, Syktyvkar, 167000
A. Moskalev
Institute of Biology, Komi Research Center, Ural Branch; Department of Biology; Moscow Institute of Physics and Technology; Vavilov Institute of General Genetics
Email: amoskalev@ib.komisc.ru
俄罗斯联邦, Syktyvkar, 167000; Syktyvkar, 167001; Dolgoprudny, Moscow region, 141707; Moscow, 119991