Molecular Variant Estimation of SLC11A1 Related Microsatellites in Chinese Indigenous Goats
- Autores: Ni W.1, E G.1, Basang W.2, Zhu Y.2, Huang Y.1
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Afiliações:
- College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University
- Institute of Animal Husbandry and Veterinary Medicine, Tibet Academy of Agriculture and Animal Husandry Science
- Edição: Volume 55, Nº 8 (2019)
- Páginas: 993-999
- Seção: Animal Genetics
- URL: https://journals.rcsi.science/1022-7954/article/view/189499
- DOI: https://doi.org/10.1134/S102279541908009X
- ID: 189499
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Resumo
The aim of this study was to investigate the polymorphism of the SLC11A1 gene in Chinese indigenous goats. A total of 215 individuals from nine goat breeds were genotyped using two pairs of known SLC11A1. Thirty-four alleles were found in these breeds across two microsatellite loci. Observed heterozygosity ranged from 0.2292 ± 0.0607 in CDB to 0.3958 ± 0.0706 in CDM. The mean number of alleles ranged from 4.50 ± 2.12 in CDB to 7.50 ± 2.12 in CDM. The coefficient of inbreeding (FIS) was lowest in CDB (0.267) and highest in DZ (0.459). All populations deviated from HWE in these two markers, except for JZ and CDM populations, which had one (EX-15). According to the FST results, only nine pairs were significantly different. Bayesian analysis using the program STRUCTURE, as well as Neighbor-joining tree analysis, both expressed 2 clusters, revealing genetic clustering patterns consistent with geographic location. In summary, the results of this study indicated that nine breeds in the Chuan-Yu area were divided into two groups according to geographical distribution. Our study may provide guidance for future research investigating marker-assisted selection and disease-resistant breeding using the SLC11A1 gene.
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Sobre autores
W.-W. Ni
College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University
Email: H67738337@swu.edu.cn
República Popular da China, Chongqing, 400716
G.-X. E
College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University
Email: H67738337@swu.edu.cn
República Popular da China, Chongqing, 400716
W.-D. Basang
Institute of Animal Husbandry and Veterinary Medicine, Tibet Academy of Agriculture and Animal Husandry Science
Email: H67738337@swu.edu.cn
República Popular da China, Lasa, 850009
Y.-B. Zhu
Institute of Animal Husbandry and Veterinary Medicine, Tibet Academy of Agriculture and Animal Husandry Science
Email: H67738337@swu.edu.cn
República Popular da China, Lasa, 850009
Y.-F. Huang
College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University
Autor responsável pela correspondência
Email: H67738337@swu.edu.cn
República Popular da China, Chongqing, 400716