Genetic characterization of Balkars and Karachays according to the variability of the Y chromosome
- Autores: Dzhaubermezov M.1, Ekomasova N.1, Litvinov S.2,3, Khusainova R.1,2, Akhmetova V.2, Balinova N.4, Khusnutdinova E.1,2
-
Afiliações:
- Department of Genetics and Fundamental Medicine
- Institute of Biochemistry and Genetics, Ufa Scientific Center
- Department of Evolutionary Biology, Institute of Molecular and Cell Biology
- Research Centre for Medical Genetics
- Edição: Volume 53, Nº 10 (2017)
- Páginas: 1152-1158
- Seção: Human Genetics
- URL: https://journals.rcsi.science/1022-7954/article/view/188494
- DOI: https://doi.org/10.1134/S1022795417100039
- ID: 188494
Citar
Resumo
The genetic diversity in two ethnic groups of the central part of the North Caucasus (Balkars and Karachays) using 50 diallelic loci in the non-recombining region of the Y chromosome was analyzed. For the first time, an analysis of distribution of frequencies of Y-chromosome haplogroups in Balkars considering different subethnic groups (Baksans, Chegems, Kholams, Bezengiyevs, and Malkars) was conducted. The major Y-chromosome haplogroups in the studied groups of Balkars and Karachays were G2a-P16 and R1a- Z2123. In addition, for a better understanding of genetic relationship between the male lineages in the studied populations and other populations of the Caucasus, we performed an analysis of R1a-M198 subhaplogroups in 22 populations of this region. The principal component analysis demonstrated that a greater difference was observed between Kholams and the other Balkar subgroups. According to the Fst analysis, Chegems, for which the prevalence of haplogroup R1b-M478 (32.2%) was reported, demonstrated the maximum difference from the other subpopulations of Balkars and Karachays.
Palavras-chave
Sobre autores
M. Dzhaubermezov
Department of Genetics and Fundamental Medicine
Autor responsável pela correspondência
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074
N. Ekomasova
Department of Genetics and Fundamental Medicine
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074
S. Litvinov
Institute of Biochemistry and Genetics, Ufa Scientific Center; Department of Evolutionary Biology, Institute of Molecular and Cell Biology
Email: murat-kbr@mail.ru
Rússia, Ufa, 450054; Tartu, 51010
R. Khusainova
Department of Genetics and Fundamental Medicine; Institute of Biochemistry and Genetics, Ufa Scientific Center
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074; Ufa, 450054
V. Akhmetova
Institute of Biochemistry and Genetics, Ufa Scientific Center
Email: murat-kbr@mail.ru
Rússia, Ufa, 450054
N. Balinova
Research Centre for Medical Genetics
Email: murat-kbr@mail.ru
Rússia, Moscow, 115478
E. Khusnutdinova
Department of Genetics and Fundamental Medicine; Institute of Biochemistry and Genetics, Ufa Scientific Center
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074; Ufa, 450054