Мақаланы E-mail арқылы жіберу Genetic control of circadian rhythms and aging
- Авторлар: Solovyov I.1,2, Dobrovol’skaya E.1, Moskalev A.1,2,3,4
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Мекемелер:
- Institute of Biology, Komi Research Center, Ural Branch
- Department of Biology
- Moscow Institute of Physics and Technology
- Vavilov Institute of General Genetics
- Шығарылым: Том 52, № 4 (2016)
- Беттер: 343-361
- Бөлім: Reviews and Theoretical Articles
- URL: https://journals.rcsi.science/1022-7954/article/view/187672
- DOI: https://doi.org/10.1134/S1022795416040104
- ID: 187672
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The review establishes a link between a group of genes which are conserved in evolution and form a molecular oscillator responsible for generation of circadian rhythms and genetic determinants of aging including associated pathways of intracellular signaling. An analysis of mechanisms of development of agedependent pathologies is conducted from the viewpoint of circadian genetics. Systematic data of circadian gene expression studies in animals demonstrating different rates of aging from accelerated to negligible are presented.
Негізгі сөздер
Авторлар туралы
I. Solovyov
Institute of Biology, Komi Research Center, Ural Branch; Department of Biology
Хат алмасуға жауапты Автор.
Email: amoskalev@ib.komisc.ru
Ресей, Syktyvkar, 167000; Syktyvkar, 167001
E. Dobrovol’skaya
Institute of Biology, Komi Research Center, Ural Branch
Email: amoskalev@ib.komisc.ru
Ресей, Syktyvkar, 167000
A. Moskalev
Institute of Biology, Komi Research Center, Ural Branch; Department of Biology; Moscow Institute of Physics and Technology; Vavilov Institute of General Genetics
Email: amoskalev@ib.komisc.ru
Ресей, Syktyvkar, 167000; Syktyvkar, 167001; Dolgoprudny, Moscow region, 141707; Moscow, 119991
