Genome-wide mapping of copy number variations in commercial hybrid pigs using a high-density SNP genotyping array
- Авторлар: Zhou L.1, Li J.1, Yang J.1, Liu C.1, Xie X.1, He Y.1, Liu X.1, Xin W.1, Zhang W.1, Ren J.1, Ma J.1, Huang L.1
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Мекемелер:
- State Key Laboratory for Pig Genetics and Production Technology
- Шығарылым: Том 52, № 1 (2016)
- Беттер: 85-92
- Бөлім: Animal Genetics
- URL: https://journals.rcsi.science/1022-7954/article/view/187622
- DOI: https://doi.org/10.1134/S1022795415120145
- ID: 187622
Дәйексөз келтіру
Аннотация
Copy number variations (CNVs) are important forms of structural variation in human and animals and can be considered as a major genetic component of phenotypic diversity. Here we used the Illumina PorcineSNP60 BeadChip V2 and a DLY [Duroc × (Large White × Landrace)] commercial hybrid population to identify 272 CNVs belonging to 165 CNV regions (CNVRs), of which 66 are new. As CNVRs are specific to origin of population, our DLY-specific data is an important complementary to the existing CNV map in the pig genome. Eight CNVRs were selected for validation by quantitative real-time PCR (qRT-PCR) and the accurate rate was high (87.25%). Gene function analysis suggested that a common CNVR may play an important role in multiple traits, including growth rate and carcass quality.
Негізгі сөздер
Авторлар туралы
L. Zhou
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
J. Li
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
J. Yang
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
C. Liu
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
X. Xie
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
Y. He
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
X. Liu
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
W. Xin
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
W. Zhang
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
J. Ren
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
J. Ma
State Key Laboratory for Pig Genetics and Production Technology
Хат алмасуға жауапты Автор.
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045
L. Huang
State Key Laboratory for Pig Genetics and Production Technology
Email: ma_junwu@hotmail.com
ҚХР, Nanchang, 330045