Genetic Characterization of Balkars and Karachays Using mtDNA Data
- Authors: Dzhaubermezov M.A.1, Ekomasova N.V.1, Reidla M.2, Litvinov S.S.3, Gabidullina L.R.1, Villems R.2,4, Khusnutdinova E.K.1,3
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Affiliations:
- Department of Genetics and Fundamental Medicine, Bashkir State University
- Institute of Genomics, University of Tartu
- Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
- Estonian Academy of Sciences
- Issue: Vol 55, No 1 (2019)
- Pages: 114-123
- Section: Human Genetics
- URL: https://journals.rcsi.science/1022-7954/article/view/189208
- DOI: https://doi.org/10.1134/S1022795419010058
- ID: 189208
Cite item
Abstract
To determine mtDNA haplogroups in the populations of Balkars (N = 235) and Karachays (N = 123), the nucleotide sequence of the hypervariable segment 1 (HVS1) and polymorphism of 20 markers of the coding region of mtDNA were analyzed. As a result of the research, 41 mtDNA haplogroups in Balkars and 33 haplogroups in Karachays were found. For the first time, the frequency distribution of mtDNA haplogroups in Balkars based on their origin to different subethnic groups (Baksans, Chegems, Kholams, Bezengivians, and Malkars) was studied. It was shown that the main mtDNA pool in the studied populations was represented by West Eurasian haplogroups. The frequencies of East Eurasian haplogroups were 10.2 and 8.9% in Balkars and Karachays, respectively. The highest value of the genetic diversity level in the studied populations was observed in Bezengivians (0.9858). The principal component analysis showed the remoteness of Baksans with respect to the first principal component from the other subethnic groups of Balkars.
About the authors
M. A. Dzhaubermezov
Department of Genetics and Fundamental Medicine, Bashkir State University
Author for correspondence.
Email: murat-kbr@mail.ru
Russian Federation, Ufa, 450074
N. V. Ekomasova
Department of Genetics and Fundamental Medicine, Bashkir State University
Email: murat-kbr@mail.ru
Russian Federation, Ufa, 450074
M. Reidla
Institute of Genomics, University of Tartu
Email: murat-kbr@mail.ru
Estonia, Tartu, 51010
S. S. Litvinov
Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
Email: murat-kbr@mail.ru
Russian Federation, Ufa, 450054
L. R. Gabidullina
Department of Genetics and Fundamental Medicine, Bashkir State University
Email: murat-kbr@mail.ru
Russian Federation, Ufa, 450074
R. Villems
Institute of Genomics, University of Tartu; Estonian Academy of Sciences
Email: murat-kbr@mail.ru
Estonia, Tartu, 51010; Tallinn, 10130
E. K. Khusnutdinova
Department of Genetics and Fundamental Medicine, Bashkir State University; Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
Email: murat-kbr@mail.ru
Russian Federation, Ufa, 450074; Ufa, 450054