Genetic Characterization of Balkars and Karachays Using mtDNA Data
- Autores: Dzhaubermezov M.1, Ekomasova N.1, Reidla M.2, Litvinov S.3, Gabidullina L.1, Villems R.2,4, Khusnutdinova E.1,3
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Afiliações:
- Department of Genetics and Fundamental Medicine, Bashkir State University
- Institute of Genomics, University of Tartu
- Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
- Estonian Academy of Sciences
- Edição: Volume 55, Nº 1 (2019)
- Páginas: 114-123
- Seção: Human Genetics
- URL: https://journals.rcsi.science/1022-7954/article/view/189208
- DOI: https://doi.org/10.1134/S1022795419010058
- ID: 189208
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Resumo
To determine mtDNA haplogroups in the populations of Balkars (N = 235) and Karachays (N = 123), the nucleotide sequence of the hypervariable segment 1 (HVS1) and polymorphism of 20 markers of the coding region of mtDNA were analyzed. As a result of the research, 41 mtDNA haplogroups in Balkars and 33 haplogroups in Karachays were found. For the first time, the frequency distribution of mtDNA haplogroups in Balkars based on their origin to different subethnic groups (Baksans, Chegems, Kholams, Bezengivians, and Malkars) was studied. It was shown that the main mtDNA pool in the studied populations was represented by West Eurasian haplogroups. The frequencies of East Eurasian haplogroups were 10.2 and 8.9% in Balkars and Karachays, respectively. The highest value of the genetic diversity level in the studied populations was observed in Bezengivians (0.9858). The principal component analysis showed the remoteness of Baksans with respect to the first principal component from the other subethnic groups of Balkars.
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Sobre autores
M. Dzhaubermezov
Department of Genetics and Fundamental Medicine, Bashkir State University
Autor responsável pela correspondência
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074
N. Ekomasova
Department of Genetics and Fundamental Medicine, Bashkir State University
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074
M. Reidla
Institute of Genomics, University of Tartu
Email: murat-kbr@mail.ru
Estônia, Tartu, 51010
S. Litvinov
Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
Email: murat-kbr@mail.ru
Rússia, Ufa, 450054
L. Gabidullina
Department of Genetics and Fundamental Medicine, Bashkir State University
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074
R. Villems
Institute of Genomics, University of Tartu; Estonian Academy of Sciences
Email: murat-kbr@mail.ru
Estônia, Tartu, 51010; Tallinn, 10130
E. Khusnutdinova
Department of Genetics and Fundamental Medicine, Bashkir State University; Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences
Email: murat-kbr@mail.ru
Rússia, Ufa, 450074; Ufa, 450054