Correlation between the presence of the VcB variable tandem repeat region and the VPI-1 pathogenicity island in Vibrio cholerae

Abstract

Primers specially designed for the purpose were used to establish the correlation between the presence of the VcB variable tandem repeat region located on chromosome II of Vibrio cholerae and the VPI-1 pathogenicity island located on chromosome I. It was demonstrated that the studied region of deletion is flanked by direct repeats and contains a gene encoding uropathogenic protein belonging to the type VI secretion system, as well as the transposase and integrase genes. The obtained results allow it to be suggested that the studied region may be a previously unknown pathogenicity islet.