Diacylglycerides as nutrition components or precursors of carcinogens: a critical view on an ambular question
- Authors: Budnevsky A.V.1, Ovsyannikov E.S.1, Popov V.I.1, Drobysheva E.S.1, Feigelman S.N.1
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Affiliations:
- Voronezh State Medical University named after N.N. Burdenko
- Issue: Vol 30, No 3 (2024)
- Pages: 249-259
- Section: Reviews
- URL: https://journals.rcsi.science/0869-2106/article/view/262449
- DOI: https://doi.org/10.17816/medjrf627498
- ID: 262449
Cite item
Abstract
Obesity is considered as a noninfectious epidemic worldwide. Metabolic disorders associated with the accumulation of adipose tissue lead to obesity-associated diabetes mellitus and cardiovascular diseases. Diet is a component of treatment of diseases associated with obesity. The most commonly used diets are caloric restriction by reducing fat in the diet. Over the years, there have been several attempts to use diacylglycerol (DAG) as components of dietary oils owing to its ability to suppress the accumulation of visceral fat and reduce postprandial levels of triacylglycerol and cholesterol and glucose in the blood serum. However, in 2009, it was found that when oil was processed at high temperatures during physical refining, DAG-enriched oil had the highest levels of potentially harmful glycidyl esters compared to conventional refined fats and oils. The study of the negative effects of glycidyl esters has prompted the food industry, which has traditionally used oil, to focus on strategies in preventing or mitigating these effects by changing the refining process or modifying deodorization equipment to reduce or eliminate process contaminants.
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##article.viewOnOriginalSite##About the authors
Andrey V. Budnevsky
Voronezh State Medical University named after N.N. Burdenko
Email: budnev@list.ru
ORCID iD: 0000-0002-1171-2746
SPIN-code: 7381-0612
ResearcherId: L-7459-2016
MD, Dr. Sci. (Medicine), professor
Russian Federation, VoronezhEvgeniy S. Ovsyannikov
Voronezh State Medical University named after N.N. Burdenko
Email: ovses@yandex.ru
ORCID iD: 0000-0002-8545-6255
SPIN-code: 7999-0433
MD, Dr. Sci. (Medicine), professor
Russian Federation, VoronezhValery I. Popov
Voronezh State Medical University named after N.N. Burdenko
Email: 9038504004@mail.ru
ORCID iD: 0000-0001-5386-9082
SPIN-code: 8896-9019
MD, Dr. Sci. (Medicine), corresponding member of RAS, professor
Russian Federation, VoronezhElena S. Drobysheva
Voronezh State Medical University named after N.N. Burdenko
Email: e.drobysheva76@mail.ru
ORCID iD: 0000-0003-2132-8374
SPIN-code: 5342-2742
MD, Cand. Sci. (Medicine), associate professor
Russian Federation, VoronezhSofia N. Feigelman
Voronezh State Medical University named after N.N. Burdenko
Author for correspondence.
Email: s.feygelman@gmail.com
ORCID iD: 0000-0003-4128-6044
SPIN-code: 1645-1203
Russian Federation, Voronezh
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