Duodenal amyloidosis: a clinical case
- Authors: Teplyakova O.V.1,2, Kharina E.A.2, Balueva O.B.1, Chernikova A.N.2, Shlikova G.I.1
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Affiliations:
- Medical Association «New Hospital»
- Ural State Medical University
- Issue: Vol 30, No 1 (2024)
- Pages: 86-93
- Section: Case reports
- URL: https://journals.rcsi.science/0869-2106/article/view/254749
- DOI: https://doi.org/10.17816/medjrf568072
- ID: 254749
Cite item
Abstract
BACKGROUND: Amyloidosis is a chronic systemic disease that, in some cases, affects the organs of the gastrointestinal tract.
CLINICAL CASE DESCRIPTION: A 62-year-old patient complained of painless enlargement of the lymph nodes in the supraclavicular region on the left side according to the puncture biopsy of the lymph node — reactive lymphoid hyperplasia. During the examination, duodenal amyloidosis was accidentally detected. The results of additional studies to determine the type of amyloid were nonspecific. The patient refused to continue the examination.
CONCLUSION: This clinical case of duodenal amyloidosis is unusual and clearly demonstrates the difficulties of diagnosis, including the absence of a clinic and the nonspecificity of the endoscopic and radiological picture during the examination. In addition, the absence of an established chronic disease characteristic of amyloid A amyloidosis and the results of laboratory and instrumental research methods, excluding amyloid light chain amyloidosis and transthyretin amyloidosis, emphasise the main role of clinicians in diagnosing the underlying disease.
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##article.viewOnOriginalSite##About the authors
Olga V. Teplyakova
Medical Association «New Hospital»; Ural State Medical University
Author for correspondence.
Email: oteplyakova69@gmail.com
ORCID iD: 0000-0003-2114-0419
SPIN-code: 3208-8679
MD, Dr. Sci. (Medicine), professor
Russian Federation, Yekaterinburg; YekaterinburgEvgeniya A. Kharina
Ural State Medical University
Email: harina-str@mail.ru
ORCID iD: 0009-0001-6540-7237
SPIN-code: 5074-5089
Russian Federation, Yekaterinburg
Olga B. Balueva
Medical Association «New Hospital»
Email: balueva_olga@list.ru
ORCID iD: 0000-0001-7252-6317
SPIN-code: 2385-8580
Russian Federation, Yekaterinburg
Alyona N. Chernikova
Ural State Medical University
Email: alyona.chernicova2014@yandex.ru
ORCID iD: 0009-0000-7482-5492
SPIN-code: 6136-2323
Russian Federation, Yekaterinburg
Galina I. Shlikova
Medical Association «New Hospital»
Email: g-i-shlykova@mail.ru
ORCID iD: 0009-0003-7948-0798
Russian Federation, Yekaterinburg
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