Duodenal amyloidosis: a clinical case
- 作者: Teplyakova O.1,2, Kharina E.2, Balueva O.1, Chernikova A.2, Shlikova G.1
-
隶属关系:
- Medical Association «New Hospital»
- Ural State Medical University
- 期: 卷 30, 编号 1 (2024)
- 页面: 86-93
- 栏目: Case reports
- URL: https://journals.rcsi.science/0869-2106/article/view/254749
- DOI: https://doi.org/10.17816/medjrf568072
- ID: 254749
如何引用文章
详细
BACKGROUND: Amyloidosis is a chronic systemic disease that, in some cases, affects the organs of the gastrointestinal tract.
CLINICAL CASE DESCRIPTION: A 62-year-old patient complained of painless enlargement of the lymph nodes in the supraclavicular region on the left side according to the puncture biopsy of the lymph node — reactive lymphoid hyperplasia. During the examination, duodenal amyloidosis was accidentally detected. The results of additional studies to determine the type of amyloid were nonspecific. The patient refused to continue the examination.
CONCLUSION: This clinical case of duodenal amyloidosis is unusual and clearly demonstrates the difficulties of diagnosis, including the absence of a clinic and the nonspecificity of the endoscopic and radiological picture during the examination. In addition, the absence of an established chronic disease characteristic of amyloid A amyloidosis and the results of laboratory and instrumental research methods, excluding amyloid light chain amyloidosis and transthyretin amyloidosis, emphasise the main role of clinicians in diagnosing the underlying disease.
关键词
作者简介
Olga Teplyakova
Medical Association «New Hospital»; Ural State Medical University
编辑信件的主要联系方式.
Email: oteplyakova69@gmail.com
ORCID iD: 0000-0003-2114-0419
SPIN 代码: 3208-8679
MD, Dr. Sci. (Medicine), professor
俄罗斯联邦, Yekaterinburg; YekaterinburgEvgeniya Kharina
Ural State Medical University
Email: harina-str@mail.ru
ORCID iD: 0009-0001-6540-7237
SPIN 代码: 5074-5089
俄罗斯联邦, Yekaterinburg
Olga Balueva
Medical Association «New Hospital»
Email: balueva_olga@list.ru
ORCID iD: 0000-0001-7252-6317
SPIN 代码: 2385-8580
俄罗斯联邦, Yekaterinburg
Alyona Chernikova
Ural State Medical University
Email: alyona.chernicova2014@yandex.ru
ORCID iD: 0009-0000-7482-5492
SPIN 代码: 6136-2323
俄罗斯联邦, Yekaterinburg
Galina Shlikova
Medical Association «New Hospital»
Email: g-i-shlykova@mail.ru
ORCID iD: 0009-0003-7948-0798
俄罗斯联邦, Yekaterinburg
参考
- Picken MM. The pathology of amyloidosis in classification: a review. Acta Haematol. 2020;143(4):322–334. doi: 10.1159/000506696
- Solonitsyn EG, Alieva IuSh, Seyfedinova SSh, et al. Amyloidosis of the gastrointestinal tract. Clinical cases. Russian Journal for Personalized Medicine. 2021;1(1):237–253. EDN: VPHHZO
- Bakulina NV, Nekrasova AS, Gudkova AYa, et al. Systemic amyloidosis: clinical manifestations and diagnosis. Jeffektivnaja farmakoterapija. 2020;16(24):68–76. EDN: YUXXON doi: 10.33978/2307-3586-2020-16-24-68-76
- Gubergrits NB, Byelyayeva NV, Mozhynа TL, Rakhmetova VS. Modern concepts of primary systemic AL-amyloidosis: the viewpoint of a gastroenterologist. Experimental and Clinical Gastroenterology Journal. 2021;(12):83–93. EDN: ECXYRK doi: 10.31146/1682-8658-ecg-196-12-83-93
- Iida T, Yamano H, Nakase H. Systemic amyloidosis with gastrointestinal involvement: diagnosis from endoscopic and histological views. J Gastroenterol Hepatol. 2018;33(3):583–590. doi: 10.1111/jgh.13996
- Muchtar E, Dispenzieri A, Magen H, et al. Systemic amyloidosis from A (AA) to T (ATTR): a review. J Intern Med. 2021;289(3):268–292. doi: 10.1111/joim.13169
- Anikonova LI, Vorobyeva OA, Bakulina NV. ATTR-amyloidosis — a systemic disease involving the kidneys. Nephrologу and Dialуsis. 2022;24(3):441–456. EDN: NPMSVG doi: 10.28996/2618-9801-2022-3-441-456
- Tereshchenko SN, Zhirov IV, Moiseeva OM, et al. Practical guidelines for the diagnosis and treatment of transthyretin amyloid cardiomyopathy (ATTR-CM or transthyretin cardiac amyloidosis). Terapevticheskii arkhiv. 2022;94(4):584–595. EDN: DYWRYZ doi: 10.26442/00403660.2022.04.201465
- Reznik EV, Nguyen TL, Ustyuzhanin DV, et al. Red flags to diagnose infiltrative cardiomyopathies. Russian Journal of Cardiology. 2023;28(S1):40–51. EDN: ZGFWNJ doi: 10.15829/1560-4071-2023-5259
- Strelkova IE. A new era in the treatment of cardiac amyloidosis: an overview of the Congress of cardiology. Lechaschi vrach. 2021;(12):90–94. EDN: RNZYNI doi: 10.51793/OS.2021.24.12.013
- Naumova ES, Nikitin SS, Adyan TA, et al. Misdiagnosed case of TTR amyloidosis in a fully investigated patient. Neuromuscular Diseases. 2018;8(1):46–52. EDN: YWZNFS doi: 10.17650/2222-8721-2018-8-1-46-52