Electrochemical Synthesis of Isoxazolines from Aldoximes and EWG Substituted Alkenes Enabling by in situ Generated Hypervalent Iodine Compounds

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Abstract

We developed the electrochemical synthesis of isoxazolines from aldoximes and EWG-substituted alkenes with the assistance of the in situ generated hypervalent iodine compounds. A wide range of substituted isoxazolines possessing fungicidal activity were obtained in 20–48% yields under constant current conditions in an undivided cell.

About the authors

O. V. Bitukov

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences; All-Russian Research Institute for Phytopathology

ORCID iD: 0000-0002-6452-0801
Moscow, Russia; B. Vyazyonny, Russia

A. S. Kirillov

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

ORCID iD: 0009-0003-3073-5702
Moscow, Russia

V. A. Vil

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

ORCID iD: 0000-0002-6847-6035
Moscow, Russia

G. I. Nikishin

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Moscow, Russia

A. O. Terent'ev

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: alterex@yandex.ru
ORCID iD: 0000-0001-8018-031X
Moscow, Russia

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