Reaction of 2-hydroxy-5-methylacetophenone chalcones with guanidine in the presence of hydrogen peroxide

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In the presented work, the reaction of two 2-hydroxy-5-methylacetophenone chalcones and guanidine was investigated in the presence of hydrogen peroxide. Depending on the structure of the chalcones a 4.6-diaryl-2-aminopyrimidine or flavanol was obtained. The structures of the obtained products were elucidated by NMR spectroscopy and X-ray crystallography. Reaction route formation of compounds was proposed.

作者简介

I. Mamedov

Baku State University

Email: bsu.nmrlab@gmail.com

V. Khrustalev

Peoples’ Friendship University of Russia (RUDN University);N.D. Zelinsky Institute of Organic Chemistry RAS

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