Epidemic season 2023–2024: the palette of ARVI pathogens in some territories of the Russian Federation and WHO regions
- Authors: Burtseva E.I.1, Breslav N.V.1, Mukasheva E.A.1, Krasnoslobodtsev K.G.1, Kirillova E.S.1, Trushakova S.V.1, Komarova I.A.2, Feodoritova E.L.1, Panova A.D.1, Kisteneva L.B.1, Khlopova I.N.1, Kruzhkova I.S.1, Krepkaia A.S.1, Morozova E.O.1, Ignatieva A.V.1, Komissarov A.B.3, Tyurin I.N.4, Samkov A.A.4, Antipjat N.A.4
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Affiliations:
- The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
- Pacific State Medical University of the Ministry of Health of the Russian Federation
- Research institute of influenza named after A.A. Smorodintsev of Ministry of Health
- Clinical Hospital for Infectious Diseases No. 1, Department of Health of Moscow
- Issue: Vol 70, No 3 (2025)
- Pages: 234-245
- Section: ORIGINAL RESEARCH
- URL: https://journals.rcsi.science/0507-4088/article/view/310661
- DOI: https://doi.org/10.36233/0507-4088-302
- EDN: https://elibrary.ru/MQXOMB
- ID: 310661
Cite item
Abstract
The purpose of this work was to determine the characteristics of the circulation of acute respiratory viral infection (ARVI) pathogens during the epidemic season of 2023–2024 in the WHO regions and Russian Federation.
Materials and methods. The article uses virological, immunological, and statistical methods, analytical material from the WHO website, to assess the circulation of ARVI pathogens in the Russian Federation and WHO regions.
Results and discussion. The detection rate of positive samples in clinical materials was as follows: influenza viruses – 7.7%, ARVI – 17.1% and SARS-CoV-2 – 6.5%. According to antigenic and molecular genetic properties, the population of the dominant subtype of the influenza A(H3N2) virus was heterogeneous and differed from the vaccine strain. The favorable sensitivity profile of epidemic strains to drugs with antineuraminidase activity (oseltamivir and zanamivir) and cap-dependent endonuclease inhibitor (baloxavir marboxil) was preserved. There was a tendency to increase the activity of respiratory pathogens such as HPIV, HAdV, HRsV, HRV, HCoV and HMPV. WHO experts have developed recommendations on the composition of influenza vaccines for the countries of the Northern and the Southern hemispheres with the replacement of the component of the influenza A(H3N2) virus: A/Darwin/9/2021 with A/Thailand/8/2022 and А/Croatia/13601RV/2023 accordingly. Cases of human infection with avian and swine influenza viruses continue to be registered.
Conclusion. Against the background of a relatively low circulation of new SARS-CoV-2 variants in the 2023-2024 season, epidemic activity of influenza viruses was recorded in the countries of the Northern hemisphere at the traditional time. Globally, its onset was associated with the influenza A(H3N2) virus, followed by an increase in the activity of the influenza A(H1N1) pdm09 virus and influenza B. As in previous seasons, differences in the proportion of influenza viruses in WHO regions, including cities of the Russian Federation, were traced.
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##article.viewOnOriginalSite##About the authors
Elena I. Burtseva
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Author for correspondence.
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-2518-6801
ScD, Head of influenza etiology and epidemiology laboratory
Russian Federation, 123098, MoscowNataliya V. Breslav
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: n.belyakova1983@gmail.com
ORCID iD: 0000-0002-6946-5119
PhD, Senior Researcher
Russian Federation, 123098, MoscowEvgenia A. Mukasheva
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: mukasheva_evgeniya@mail.ru
ORCID iD: 0000-0002-5688-5309
Research Associate
Russian Federation, 123098, MoscowKirill G. Krasnoslobodtsev
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: kkg_87@mail.ru
ORCID iD: 0000-0003-1745-9128
Research Associate
Russian Federation, 123098, MoscowElena S. Kirillova
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: esshevchenko@yandex.ru
ORCID iD: 0000-0001-7977-7530
PhD, Leading Researcher
Russian Federation, 123098, MoscowSvetlana V. Trushakova
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: s.trushakova@gmail.com
ORCID iD: 0000-0002-9610-3041
PhD, Senior Researcher
Russian Federation, 123098, MoscowIrina A. Komarova
Pacific State Medical University of the Ministry of Health of the Russian Federation
Email: mikhaira@yandex.ru
ORCID iD: 0000-0003-0483-7433
Assistant of the Department of Infectious Diseases
Russian Federation, 690002, Primorsky Krai, VladivostokElena L. Feodoritova
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: flulab@mail.ru
ORCID iD: 0000-0002-1472-1357
Research Associate
Russian Federation, 123098, MoscowAnna D. Panova
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: ainushgnomello@gmail.com
ORCID iD: 0000-0002-9322-6273
junior research assistant
Russian Federation, 123098, MoscowLidiya B. Kisteneva
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: lborisovna2007@yandex.ru
ORCID iD: 0000-0001-7336-409X
head of laboratory
Russian Federation, 123098, MoscowIrina N. Khlopova
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: khlopova.ira@yandex.ru
ORCID iD: 0000-0002-7419-590X
PhD, Leading Researcher
Russian Federation, 123098, MoscowIrina S. Kruzhkova
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: irina-kru@yandex.ru
ORCID iD: 0000-0002-1983-481X
junior research assistant
Russian Federation, 123098, MoscowAnastasia S. Krepkaia
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: nastya18-96@mail.ru
ORCID iD: 0000-0002-7272-4011
junior research assistant
Russian Federation, 123098, MoscowEkaterina O. Morozova
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: eo-morozova@inbox.ru
ORCID iD: 0009-0001-3367-6168
PhD, Senior Researcher
Russian Federation, 123098, MoscowAnna V. Ignatieva
The N.F. Gamaleya Research Center of Epidemiology and Microbiology of Ministry of Health
Email: valgella@yandex.ru
ORCID iD: 0000-0001-6206-2299
PhD, Senior Researcher
Russian Federation, 123098, MoscowAndrey B. Komissarov
Research institute of influenza named after A.A. Smorodintsev of Ministry of Health
Email: andrey.komissarov@influenza.spb.ru
ORCID iD: 0000-0003-1733-1255
Head of the Laboratory of Molecular Virology
Russian Federation, 197022, St. PetersburgIgor N. Tyurin
Clinical Hospital for Infectious Diseases No. 1, Department of Health of Moscow
Email: tyurin.dti@yandex.ru
ORCID iD: 0000-0002-5696-1586
PhD, Chief Physician
Russian Federation, 125367, MoscowAleksey A. Samkov
Clinical Hospital for Infectious Diseases No. 1, Department of Health of Moscow
Email: a.a.samkov@yandex.ru
ORCID iD: 0000-0002-0365-3096
Deputy Chief Medical Officer
Russian Federation, 125367, MoscowNataliya A. Antipjat
Clinical Hospital for Infectious Diseases No. 1, Department of Health of Moscow
Email: natadoc70@bk.ru
ORCID iD: 0000-0001-8578-2838
Deputy Chief Medical Officer
Russian Federation, 125367, MoscowReferences
- Burtseva E.I., Kolobukhina L.V., Voronina O.L., Ignatjeva A.V., Mukasheva E.A., Panova A.D., et al. Features of the circulation of ARVI pathogens during of emergence and widespread of SARS-CoV-2 in the 2018–2021. Epidemiologiya i Vaktsinoprofilaktika. 2022; 21(4): 16–26. https://doi.org/10.31631/2073-3046-2022-21-4-16-26 https://elibrary.ru/rnyfoi (in Russian)
- Burtseva E.I., Kolobukhina L.V., Panova A.D., Mukasheva E.A., Krasnoslobodtsev K.G., Kirillova E.S., et al. Properties of influenza viruses that caused epidemic increases in morbidity in Russia and countries of the world during 2022–2023. The effectiveness of vaccine prophylaxis. The effectiveness of vaccine prophylaxis. Voprosy virusologii. 2024; 69(1): 42–55. https://doi.org/10.36233/0507-4088-211 https://elibrary.ru/zqtfnx (in Russian)
- Sominina A.A., Danilenko D.M., Komissarov A.B., Pisareva M.M., Musaeva T.D., Stolyarov K.A., et al. Changes in the etiological structure of severe acute respiratory viral infections in children and adults under the influence of the COVID-19 pandemic. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 2024; 101(3): 327–41. https://doi.org/10.36233/0372-9311-532 https://elibrary.ru/jmtwkj (in Russian)
- Petrova P.A., Konovalova N.I., Boyarintseva A.Y., Danilenko D.M., Vasilieva A.D., Shelepanova T.N., et al. Etiologic characteristics of influenza epidemics on the territory of Russia in the period of pandemic COVID-19 in 2020–2023. Epidemiologiya i Vaktsinoprofilaktika. 2024; 23(3): 88–97. https://doi.org/10.31631/2073-3046-2024-23-3-88-97 https://elibrary.ru/ofrzhj (in Russian)
- Karpova L.S., Pelikh M.Yu., Popovtseva N.M., Stolyarova T.P., Volik K.M., Stolyarov K.A. Coronavirus infection caused by the omicron variant and its daughter genovariants in Russia (2022–2023). Epidemiologiya i Vaktsinoprofilaktika. 2024; 23(2): 36–49. https://doi.org/10.31631/2073-3046-2024-23-2-36-49 https://elibrary.ru/uqdnmi (in Russian)
- Karpova L.S., Komissarov A.B., Stolyarov K.A., Popovtseva N.M., Stolyarova T.P., Pelikh M.Yu., et al. Features of the COVID-19 Epidemic Process in Each of the of the Five Waves of Morbidity in Russia. Epidemiologiya i Vaktsinoprofilaktika. 2023; 22(2): 23–36. https://doi.org/10.31631/2073-3046-2023-22-2-23-36 https://elibrary.ru/udxfrp (in Russian)
- Pshenichnaya N.Yu., ed. Influenza and Acute Respiratory Viral Infections in the XXI Century: A Guide for Doctors [Gripp i ORVI v XXI veke: rukovodstvo dlya vrachei]. Moscow: GEOTAR-Media; 2024. https://doi.org/10.33029/9704-8433-3-IAR-2024-1-304 (in Russian)
- Zhou B., Lin X., Wang W., Halpin R.A., Bera J., Stockwell T.B., et al. Universal influenza B virus genomic amplification facilitates, sequencing, diagnostics, and reverse genetics. J. Clin. Microbiol. 2014; 52(5): 1330–7. https://doi.org/10.1128/jcm.03265-13
- Zhou B., Donnelly M.E., Scholes D.T., St George K., Hatta M., Kawaoka Y., et al. Single-reaction genomic amplification accelerates sequencing and vaccine production for classical and swine origin human influenza A viruses. J. Virol. Oct. 2009; 83(19): 10309–13. https://doi.org/10.1128/jvi.01109-09
- Charostad J., Rezaei Zadeh Rukerd M., Mahmoudvand S., Bashash D., Hashemi S.M.A., Nakhaie M., et al. A comprehensive review of highly pathogenic avian influenza (HPAI) H5N1: An imminent threat at doorstep. Travel Med. Infect. Dis. 2023; 55: 102638. https://doi.org/10.1016/j.tmaid.2023.102638
- Belser J.A., Sun X., Pulit-Penaloza J.A., Maines T.R. Fatal infection in ferrets after ocular inoculation with highly pathogenic avian influenza A(H5N1) virus. Emerg. Infect. Dis. 2024; 30(7): 1484–7. https://doi.org/10.3201/eid3007.240520
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