Current diagnostics and biomarkers for arboviral infections (a review on Dengue, Zika, West Nile and Chikungunya viruses)
- Authors: Adekola H.A.1, Wahab K.A.1, Odunsi O.E.1, Abesin T.A.1, Oyesanya O.A.1
-
Affiliations:
- Olabisi Onabanjo University
- Issue: Vol 69, No 1 (2024)
- Pages: 31-41
- Section: REVIEWS
- URL: https://journals.rcsi.science/0507-4088/article/view/254057
- DOI: https://doi.org/10.36233/0507-4088-209
- EDN: https://elibrary.ru/zqtfnx
- ID: 254057
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Abstract
Arboviral infections, transmitted to humans primarily through arthropod vectors, constitute a significant global health threat. Arboviruses, such as Dengue, Zika, Chikungunya, and West Nile viruses, continue to cause widespread outbreaks, necessitating advanced diagnostic tools. Emerging technologies including Lab On A Chip (LOC), Lab On A Disc (LOAD), Microfluidic Paper-Based Analytical Devices (µPADS), Lateral Flow Devices, CRISPR-CAS 12/13, Quartz crystal microbalance (QCM), and Nano-Technology are evaluated for their potential to enhance arboviral diagnosis, offering rapid, accurate, and point-of-care solutions. Furthermore, the identification of robust biomarkers, including Inflammatory Cytokines, Antibodies, Endothelial Activation Products and Indicators of Tissue or Organ Damage, is crucial for improving the understanding of disease pathogenesis, prognosis, and treatment response. A comprehensive analysis of potential diagnostics and biomarkers for arboviral infections sheds light on the evolving strategies to combat these medically significant diseases, ultimately contributing to more effective surveillance, diagnosis and management worldwide.
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##article.viewOnOriginalSite##About the authors
Hafeez A. Adekola
Olabisi Onabanjo University
Author for correspondence.
Email: haderinsayor@gmail.com
ORCID iD: 0000-0003-3132-3315
University lecturer, PhD, Medical Microbiology and Public Health, Olabisi Onabanjo University
Nigeria, Ago IwoyeKareem A. Wahab
Olabisi Onabanjo University
Email: wahabkareem273@gmail.com
ORCID iD: 0009-0002-9542-3817
Graduate BSc (Hons) Microbiology, Olabisi Onabanjo University
Nigeria, Ago IwoyeOmotayo E. Odunsi
Olabisi Onabanjo University
Email: odunsiomotayo17@gmail.com
ORCID iD: 0009-0001-2653-4401
Graduate BSc (Hons) Microbiology, Olabisi Onabanjo University
Nigeria, Ago IwoyeTobiloba A. Abesin
Olabisi Onabanjo University
Email: tobishin98@gmail.com
Graduate BSc (Hons) Microbiology, Olabisi Onabanjo University
Nigeria, Ago IwoyeOluwaseun A. Oyesanya
Olabisi Onabanjo University
Email: Oluwaseunoyesanya2018@gmail.com
ORCID iD: 0009-0007-1474-9679
Graduate BSc (Hons) Microbiology, Olabisi Onabanjo University
Nigeria, Ago IwoyeReferences
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