Animal delta-like viruses (Kolmioviridae: Deltavirus) and the origin of the human hepatitis D virus (HDV)

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Abstract

Hepatitis D (delta, δ) virus (HDV) was discovered more than 40 years ago, but the understanding of its origin and evolution is poor. This is mainly due to the lack, until recently, of data on the existence of any viruses similar to HDV. The discovery in recent years of sequences of new delta-like agents in a wide range of vertebrate (Vertebrata) and invertebrate (Invertebrata) species has facilitated a revision of views on the origin of HDV and contributed to understanding the place of this unique virus among other animals’ viral agents. The purpose of this review is to analyze the latest published data on new delta-like agents and their biological characteristics.

About the authors

O. V. Isaeva

FSBSI «I.I. Mechnikov Research Institute of Vaccines and Sera»; FSBEI FPE «Russian Medical Academy of Continuous Professional Education» of the Ministry of Health of Russia

Author for correspondence.
Email: isaeva.06@mail.ru
ORCID iD: 0000-0002-2656-3667

Ol’ga V. Isaeva, Ph.D. (Biol.), Lead Researcher of the Viral Hepatitis Laboratory; Lead Researcher of the Molecular and Personalized Medicine Research Institute

105064, Moscow, Russia

125993, Moscow, Russia

Russian Federation

K. K. Kyuregyan

FSBSI «I.I. Mechnikov Research Institute of Vaccines and Sera»; FSBEI FPE «Russian Medical Academy of Continuous Professional Education» of the Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0002-3599-117X

105064, Moscow, Russia

125993, Moscow, Russia

Russian Federation

M. I. Mikhailov

FSBSI «I.I. Mechnikov Research Institute of Vaccines and Sera»; FSBEI FPE «Russian Medical Academy of Continuous Professional Education» of the Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0002-6636-6801

105064, Moscow, Russia

125993, Moscow, Russia

Russian Federation

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Copyright (c) 2021 Isaeva O.V., Kyuregyan K.K., Mikhailov M.I.

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